DC Field | Value | Language |
---|---|---|
dc.contributor.author | 권태윤 | ko |
dc.contributor.author | 정현태 | ko |
dc.contributor.author | 조영빈 | ko |
dc.contributor.author | 신현정 | ko |
dc.date.accessioned | 2022-12-11T05:02:38Z | - |
dc.date.available | 2022-12-11T05:02:38Z | - |
dc.date.created | 2022-12-11 | - |
dc.date.created | 2022-12-11 | - |
dc.date.created | 2022-12-11 | - |
dc.date.issued | 2022-07 | - |
dc.identifier.citation | 한국가시화정보학회지, v.20, no.2, pp.70 - 77 | - |
dc.identifier.issn | 1598-8430 | - |
dc.identifier.uri | http://hdl.handle.net/10203/302710 | - |
dc.description.abstract | Skeletal muscle tissues feature cellular heterogeneity, including differentiated myofibers, myoblasts, and satellite cells. Thanks to the presence of undifferentiated myoblasts and satellite cells, skeletal muscle tissues can self-regenerate after injury. In skeletal muscle regeneration, the collective motions among these cell types must play a significant role, but little is known about the dynamic collective behavior during the regeneration. In this study, we constructed in vitro platform to visualize the migration behavior of skeletal muscle cells in specific conditions that mimic the biochemical environment of injured skeletal muscles. We then visualized the spatiotemporal distribution of stresses arising from the differential collectiveness in the cellular clusters under different conditions. From these analyses, we identified that the heterogeneous population of muscle cells exhibited distinct collective migration patterns in the injury-mimicking condition, suggesting selective activation of a specific cell type by the biochemical cues from the injured skeletal muscles. | - |
dc.language | Korean | - |
dc.publisher | 한국가시화정보학회 | - |
dc.title | 골격근 손상 및 재생 환경에서의 근육 세포 군집 이동의 물리적 특성 가시화 | - |
dc.title.alternative | Visualization of the physical characteristics of collective myoblast migration upon skeletal muscle injury and regeneration environment | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.citation.volume | 20 | - |
dc.citation.issue | 2 | - |
dc.citation.beginningpage | 70 | - |
dc.citation.endingpage | 77 | - |
dc.citation.publicationname | 한국가시화정보학회지 | - |
dc.identifier.kciid | ART002865146 | - |
dc.contributor.localauthor | 신현정 | - |
dc.description.isOpenAccess | N | - |
dc.subject.keywordAuthor | 골격근 | - |
dc.subject.keywordAuthor | 골격근 손상 및 재생 | - |
dc.subject.keywordAuthor | 세포 견인력 분석법 | - |
dc.subject.keywordAuthor | 세포간 응력 분석법 | - |
dc.subject.keywordAuthor | Skeletal muscle | - |
dc.subject.keywordAuthor | Skeletal muscle injury and regeneration | - |
dc.subject.keywordAuthor | Traction force microscopy | - |
dc.subject.keywordAuthor | Monolayer stress microscopy | - |
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