DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Soo Hyun | ko |
dc.contributor.author | Kim, Sunho | ko |
dc.contributor.author | Yang, Jun-Yeong | ko |
dc.contributor.author | Mun, ChaeWon | ko |
dc.contributor.author | Lee, Seunghun | ko |
dc.contributor.author | Kim, Shin-Hyun | ko |
dc.contributor.author | Park, Sung-Gyu | ko |
dc.date.accessioned | 2022-02-08T06:46:58Z | - |
dc.date.available | 2022-02-08T06:46:58Z | - |
dc.date.created | 2022-01-17 | - |
dc.date.created | 2022-01-17 | - |
dc.date.created | 2022-01-17 | - |
dc.date.issued | 2022-01 | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v.23, no.2 | - |
dc.identifier.issn | 1661-6596 | - |
dc.identifier.uri | http://hdl.handle.net/10203/292151 | - |
dc.description.abstract | Effective hotspot engineering with facile and cost-effective fabrication procedures is critical for the practical application of surface-enhanced Raman spectroscopy (SERS). We propose a SERS substrate composed of a metal film over polyimide nanopillars (MFPNs) with three-dimensional (3D) volumetric hotspots for this purpose. The 3D MFPNs were fabricated through a two-step process of maskless plasma etching and hydrogel encapsulation. The probe molecules dispersed in solution were highly concentrated in the 3D hydrogel networks, which provided a further enhancement of the SERS signals. SERS performance parameters such as the SERS enhancement factor, limit-of-detection, and signal reproducibility were investigated with Cyanine5 (Cy5) acid Raman dye solutions and were compared with those of hydrogel-free MFPNs with two-dimensional hotspots. The hydrogel-coated MFPNs enabled the reliable detection of Cy5 acid, even when the Cy5 concentration was as low as 100 pM. We believe that the 3D volumetric hotspots created by introducing a hydrogel layer onto plasmonic nanostructures demonstrate excellent potential for the sensitive and reproducible detection of toxic and hazardous molecules. | - |
dc.language | English | - |
dc.publisher | MDPI | - |
dc.title | Hydrogel-assisted 3D volumetric hotspot for sensitive detection by surface-enhanced Raman spectroscopy | - |
dc.type | Article | - |
dc.identifier.wosid | 000747840900001 | - |
dc.identifier.scopusid | 2-s2.0-85122816530 | - |
dc.type.rims | ART | - |
dc.citation.volume | 23 | - |
dc.citation.issue | 2 | - |
dc.citation.publicationname | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.identifier.doi | 10.3390/ijms23021004 | - |
dc.contributor.localauthor | Kim, Shin-Hyun | - |
dc.contributor.nonIdAuthor | Lee, Soo Hyun | - |
dc.contributor.nonIdAuthor | Yang, Jun-Yeong | - |
dc.contributor.nonIdAuthor | Mun, ChaeWon | - |
dc.contributor.nonIdAuthor | Lee, Seunghun | - |
dc.contributor.nonIdAuthor | Park, Sung-Gyu | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | surface-enhanced Raman spectroscopyvolumetric hotspot engineeringmaskless plasma etchinghydrogel encapsulation | - |
dc.subject.keywordPlus | GOLD NANOPARTICLESSCATTERINGNANOSTRUCTURESPOLYMERSGLUCOSEUNIFORMARRAYS | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.