DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yang, Ji Ae | ko |
dc.contributor.author | Lee, Jeong Seok | ko |
dc.contributor.author | Park, Jin Kyun | ko |
dc.contributor.author | Lee, Eun Bong | ko |
dc.contributor.author | Song, Yeong Wook | ko |
dc.contributor.author | Lee, Eun Young | ko |
dc.date.accessioned | 2022-01-06T06:40:42Z | - |
dc.date.available | 2022-01-06T06:40:42Z | - |
dc.date.created | 2022-01-06 | - |
dc.date.created | 2022-01-06 | - |
dc.date.issued | 2019-03 | - |
dc.identifier.citation | KOREAN JOURNAL OF INTERNAL MEDICINE, v.34, no.2, pp.434 - 441 | - |
dc.identifier.issn | 1226-3303 | - |
dc.identifier.uri | http://hdl.handle.net/10203/291617 | - |
dc.description.abstract | Background/Aims: To analyze clinical characteristics of interstitial lung disease (ILD) associated with rheumatoid arthritis (RA), especially in patients with poor prognosis. Methods: Seventy-seven RA patients with ILD and 231 age, sex, and disease duration-matched RA patients without ILD were enrolled in this retrospective study. Epidemiologic, clinical, and laboratory information were obtained through a medical chart review. Logistic regression analysis was used to estimate the risk of mortality in RA patients with ILD. Results: Compared to the RA without ILD group, the RA with ILD group had significantly higher titers of rheumatoid factor and the anti-cyclic citrullinated peptide (p = 0.001 for both), higher levels of C-reactive protein (CRP) at the time of RA diagnosis (p = 0.014), and a higher erythrocyte sedimentation rate (p = 0.022) and CRP levels (p < 0.001) throughout the 10-year follow-up period. These patients also received a higher mean daily dose of corticosteroids (p < 0.001). In the subgroup analysis of RA patients with ILD, 28 patients (36.4%) died during follow-up. Multivariate analysis revealed that older age at the time of ILD diagnosis was significantly associated with mortality. Usual interstitial pneumonia (UIP) subtype on high-resolution computed tomography (HRCT) was also suggested as a poor prognostic factor. Conclusions: The survival of RA patients with ILD is adversely affected by age at the time of ILD diagnosis. RA-ILD patients diagnosed after age 65 or with a UIP subtype on HRCT may have a poor prognosis. | - |
dc.language | English | - |
dc.publisher | KOREAN ASSOC INTERNAL MEDICINE | - |
dc.title | Clinical characteristics associated with occurrence and poor prognosis of interstitial lung disease in rheumatoid arthritis | - |
dc.type | Article | - |
dc.identifier.wosid | 000459694200023 | - |
dc.identifier.scopusid | 2-s2.0-85062600288 | - |
dc.type.rims | ART | - |
dc.citation.volume | 34 | - |
dc.citation.issue | 2 | - |
dc.citation.beginningpage | 434 | - |
dc.citation.endingpage | 441 | - |
dc.citation.publicationname | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.identifier.doi | 10.3904/kjim.2016.349 | - |
dc.contributor.localauthor | Lee, Jeong Seok | - |
dc.contributor.nonIdAuthor | Yang, Ji Ae | - |
dc.contributor.nonIdAuthor | Park, Jin Kyun | - |
dc.contributor.nonIdAuthor | Lee, Eun Bong | - |
dc.contributor.nonIdAuthor | Song, Yeong Wook | - |
dc.contributor.nonIdAuthor | Lee, Eun Young | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Arthritis | - |
dc.subject.keywordAuthor | rheumatoid | - |
dc.subject.keywordAuthor | Lung diseases | - |
dc.subject.keywordAuthor | interstitial | - |
dc.subject.keywordAuthor | Rheumatoid arthritis-associated interstitial lung disease | - |
dc.subject.keywordPlus | C-REACTIVE PROTEIN | - |
dc.subject.keywordPlus | CLASSIFICATION | - |
dc.subject.keywordPlus | PNEUMONIA | - |
dc.subject.keywordPlus | RISK | - |
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