The epigenome: the next substrate for engineering
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Park, Minhee | ko |
| dc.contributor.author | Keung, Albert J. | ko |
| dc.contributor.author | Khalil, Ahmad S. | ko |
| dc.date.accessioned | 2021-11-15T06:40:28Z | - |
| dc.date.available | 2021-11-15T06:40:28Z | - |
| dc.date.created | 2021-11-15 | - |
| dc.date.created | 2021-11-15 | - |
| dc.date.created | 2021-11-15 | - |
| dc.date.issued | 2016-08 | - |
| dc.identifier.citation | GENOME BIOLOGY, v.17 | - |
| dc.identifier.issn | 1474-760X | - |
| dc.identifier.uri | http://hdl.handle.net/10203/289163 | - |
| dc.description.abstract | We are entering an era of epigenome engineering. The precision manipulation of chromatin and epigenetic modifications provides new ways to interrogate their influence on genome and cell function and to harness these changes for applications. We review the design and state of epigenome editing tools, highlighting the unique regulatory properties afforded by these systems. | - |
| dc.language | English | - |
| dc.publisher | BIOMED CENTRAL LTD | - |
| dc.title | The epigenome: the next substrate for engineering | - |
| dc.type | Article | - |
| dc.identifier.wosid | 000383428100002 | - |
| dc.identifier.scopusid | 2-s2.0-84984685513 | - |
| dc.type.rims | ART | - |
| dc.citation.volume | 17 | - |
| dc.citation.publicationname | GENOME BIOLOGY | - |
| dc.identifier.doi | 10.1186/s13059-016-1046-5 | - |
| dc.contributor.localauthor | Park, Minhee | - |
| dc.contributor.nonIdAuthor | Keung, Albert J. | - |
| dc.contributor.nonIdAuthor | Khalil, Ahmad S. | - |
| dc.description.isOpenAccess | N | - |
| dc.type.journalArticle | Review | - |
| dc.subject.keywordPlus | DNA METHYLATION PATTERNS | - |
| dc.subject.keywordPlus | ZINC-FINGER NUCLEASES | - |
| dc.subject.keywordPlus | HISTONE H3 | - |
| dc.subject.keywordPlus | HUMAN-CELLS | - |
| dc.subject.keywordPlus | IN-VIVO | - |
| dc.subject.keywordPlus | SYNTHETIC BIOLOGY | - |
| dc.subject.keywordPlus | TRANSCRIPTIONAL REPRESSION | - |
| dc.subject.keywordPlus | CHROMATIN MODIFICATIONS | - |
| dc.subject.keywordPlus | EPIGENETIC REGULATION | - |
| dc.subject.keywordPlus | BINDING-SPECIFICITY | - |
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