A soft and transparent contact lens for the wireless quantitative monitoring of intraocular pressure

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dc.contributor.authorKim, Jooheeko
dc.contributor.authorPark, Jihunko
dc.contributor.authorPark, Young-Geunko
dc.contributor.authorCha, Eunkyungko
dc.contributor.authorKu, Minjaeko
dc.contributor.authorAn, Hyeon Seokko
dc.contributor.authorLee, Kyoung-Pilko
dc.contributor.authorHuh, Man-Ilko
dc.contributor.authorKim, Junmoko
dc.contributor.authorKim, Taek-Sooko
dc.contributor.authorKim, Dai Wooko
dc.contributor.authorKim, Hong Kyunko
dc.contributor.authorPark, Jang-Ungko
dc.date.accessioned2021-07-30T00:31:03Z-
dc.date.available2021-07-30T00:31:03Z-
dc.date.created2021-05-25-
dc.date.issued2021-07-
dc.identifier.citationNATURE BIOMEDICAL ENGINEERING, v.5, no.7, pp.772 - 782-
dc.identifier.issn2157-846X-
dc.identifier.urihttp://hdl.handle.net/10203/286932-
dc.description.abstractA soft and transparent contact lens can be used to wirelessly monitor intraocular pressure quantitatively in humans. Continuous detection of raised intraocular pressure (IOP) could benefit the monitoring of patients with glaucoma. Current contact lenses with embedded sensors for measuring IOP are rigid, bulky, partially block vision or are insufficiently sensitive. Here, we report the design and testing in volunteers of a soft and transparent contact lens for the quantitative monitoring of IOP in real time using a smartphone. The contact lens incorporates a strain sensor, a wireless antenna, capacitors, resistors, stretchable metal interconnects and an integrated circuit for wireless communication. In rabbits, the lens provided measurements that match those of a commercial tonometer. In ten human participants, the lens proved to be safe, and reliably provided accurate quantitative measurements of IOP without inducing inflammation.-
dc.languageEnglish-
dc.publisherNATURE RESEARCH-
dc.titleA soft and transparent contact lens for the wireless quantitative monitoring of intraocular pressure-
dc.typeArticle-
dc.identifier.wosid000646523800006-
dc.identifier.scopusid2-s2.0-85105338299-
dc.type.rimsART-
dc.citation.volume5-
dc.citation.issue7-
dc.citation.beginningpage772-
dc.citation.endingpage782-
dc.citation.publicationnameNATURE BIOMEDICAL ENGINEERING-
dc.identifier.doi10.1038/s41551-021-00719-8-
dc.contributor.localauthorKim, Taek-Soo-
dc.contributor.nonIdAuthorKim, Joohee-
dc.contributor.nonIdAuthorPark, Jihun-
dc.contributor.nonIdAuthorPark, Young-Geun-
dc.contributor.nonIdAuthorCha, Eunkyung-
dc.contributor.nonIdAuthorKu, Minjae-
dc.contributor.nonIdAuthorAn, Hyeon Seok-
dc.contributor.nonIdAuthorLee, Kyoung-Pil-
dc.contributor.nonIdAuthorHuh, Man-Il-
dc.contributor.nonIdAuthorKim, Dai Woo-
dc.contributor.nonIdAuthorKim, Hong Kyun-
dc.contributor.nonIdAuthorPark, Jang-Ung-
dc.description.isOpenAccessN-
dc.type.journalArticleArticle-
dc.subject.keywordPlusSTRAIN SENSOR-
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