DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Park, Chan-Kyu | - |
dc.contributor.advisor | Chung, Jong-Kyoung | - |
dc.contributor.advisor | 박찬규 | - |
dc.contributor.advisor | 정종경 | - |
dc.contributor.author | Kang, Ho-Young | - |
dc.contributor.author | 강호영 | - |
dc.date.accessioned | 2011-12-12T09:01:03Z | - |
dc.date.available | 2011-12-12T09:01:03Z | - |
dc.date.issued | 1997 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=112645&flag=dissertation | - |
dc.identifier.uri | http://hdl.handle.net/10203/28508 | - |
dc.description | 학위논문(석사) - 한국과학기술원 : 생물과학과, 1997.2, [ iv, 53 p. ] | - |
dc.description.abstract | During the study on transcriptional regulation of Escherichia coli K-12 ribose (rbs) operon, it was observed that the operon is repressed by the presence of D-xylose. However, the other sugars examined except D-glucose had little effect on the expression of the rbs operon and the xylose(xyl) operon was not affected by the presence of D-ribose. Genetic analysis and β-galactosidase assay revealed that XylR, a regulator of the xylose operon, was responsible for the repression. {\it E.coli} cells also showed a diauxic growth, which is typical in the catabolite repression by D-glucose, in minimal medium containing D-xylose plus D-ribose. These results led us to the conclusion that there exists novel mechanism of catabolite repression in the rbs operon that is exerted by D-xylose through the action of XylR. Furthermore, it was shown that the xyl and rbs operon were repressed by the presence of L-arabinose whereas the arabinose operon was not affected by D-xylose or D-ribose, suggesting that there exists a mechanism determining the preference of pentose utilization at the level of transcription. | eng |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.subject | Catabolite repression | - |
dc.subject | Pentose | - |
dc.subject | 대사산물억제 | - |
dc.subject | 오탄당 | - |
dc.title | Novel mechanism of catabolite repression that exists in the pentose operons of escherichia coli K-12 | - |
dc.title.alternative | 대장균 오탄당 오페론에 존재하는 새로운 대사산물 억제 기작 | - |
dc.type | Thesis(Master) | - |
dc.identifier.CNRN | 112645/325007 | - |
dc.description.department | 한국과학기술원 : 생물과학과, | - |
dc.identifier.uid | 000953014 | - |
dc.contributor.localauthor | Park, Chan-Kyu | - |
dc.contributor.localauthor | Chung, Jong-Kyoung | - |
dc.contributor.localauthor | 박찬규 | - |
dc.contributor.localauthor | 정종경 | - |
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