DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Daesoo Kim | - |
dc.contributor.advisor | 김대수 | - |
dc.contributor.author | Jung, DaJung | - |
dc.date.accessioned | 2021-05-12T19:42:14Z | - |
dc.date.available | 2021-05-12T19:42:14Z | - |
dc.date.issued | 2020 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=913347&flag=dissertation | en_US |
dc.identifier.uri | http://hdl.handle.net/10203/284271 | - |
dc.description | 학위논문(박사) - 한국과학기술원 : 생명과학과, 2020.2,[v,68 p. :] | - |
dc.description.abstract | The dentate gyrus (DG) is known to be critical for detecting changes in environments, however the specific roles of main excitatory cell types of DG: granule cells (GC) and mossy cells (MC) are still unknown. Here we designed reusable optoelectronic probe for chronic single unit recording and optogenetic manipulations. By implementing optogenetic labeling using this tool, I was able to identify electrophysiological features of GCs and MCs. I observe that fixing a new object, while mice running on the familiar belt, induces a distinct GC and MC response, with maximal alteration near the new object. In general, MCs response is stronger and peaks earlier than GCs. These results suggest that MC spread information about change to GC network thus helping for pattern separation. | - |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.subject | Dentate gyrus▼aMossy cell▼aGranule cell▼achronic recording▼amicro-drive▼aoptogenetics | - |
dc.subject | 치상회▼a이끼세포▼a과립세포▼a장기 레코딩▼a마이크로드라이브▼a광유전학 | - |
dc.title | Encoding new spatial information by optogenetically identified mossy and granule cell in the Dentate gyrus | - |
dc.title.alternative | 광유전학으로 확인한 치상회의 이끼세포와 과립세포 의 새로운 공간 정보 처리반응 연구 | - |
dc.type | Thesis(Ph.D) | - |
dc.identifier.CNRN | 325007 | - |
dc.description.department | 한국과학기술원 :생명과학과, | - |
dc.contributor.alternativeauthor | 정다정 | - |
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