Immunostimulating effect of resiquimod-PLGA nanoparticles coated on microneedle with inactivated influenza마이크로니들을 이용한 인플루엔자 백신과 면역증강제의 피부 전달 연구
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | Kim, Yeu Chun | - |
| dc.contributor.advisor | 김유천 | - |
| dc.contributor.author | Lee, Hyo Won | - |
| dc.date.accessioned | 2021-05-11T19:32:26Z | - |
| dc.date.available | 2021-05-11T19:32:26Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=875284&flag=dissertation | en_US |
| dc.identifier.uri | http://hdl.handle.net/10203/282990 | - |
| dc.description | 학위논문(석사) - 한국과학기술원 : 생명화학공학과, 2019.8,[41 p. :] | - |
| dc.description.abstract | Pandemic influenza especially damaged young host, therefore safe vaccination methods without severe infection have been studied. Accordingly, adjuvants were examined to induce desired immune responses to minimal dosage of antigen. In this thesis, novel adjuvants that can be used for immunization through skin by microneedle is screened, and the effect on the antibody, cytokine production, and protection against homologous virus is confirmed in a mouse model. | - |
| dc.language | eng | - |
| dc.publisher | 한국과학기술원 | - |
| dc.subject | Microneedle▼avaccine▼aadjuvant▼aresiquimod▼ananoparticle | - |
| dc.subject | 마이크로니들▼a백신▼a면역증강제▼a레지퀴모드▼a나노파티클 | - |
| dc.title | Immunostimulating effect of resiquimod-PLGA nanoparticles coated on microneedle with inactivated influenza | - |
| dc.title.alternative | 마이크로니들을 이용한 인플루엔자 백신과 면역증강제의 피부 전달 연구 | - |
| dc.type | Thesis(Master) | - |
| dc.identifier.CNRN | 325007 | - |
| dc.description.department | 한국과학기술원 :생명화학공학과, | - |
| dc.contributor.alternativeauthor | 이효원 | - |
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