DC Field | Value | Language |
---|---|---|
dc.contributor.author | An, Won | ko |
dc.contributor.author | Choi, Su Bin | ko |
dc.contributor.author | Kim, Namhoon | ko |
dc.contributor.author | Kwon, Na Yeon | ko |
dc.contributor.author | Ghosh, Prithwish | ko |
dc.contributor.author | Han, Sang Hoon | ko |
dc.contributor.author | Mishra, Neeraj Kumar | ko |
dc.contributor.author | Han, Sangil | ko |
dc.contributor.author | Hong, Sungwoo | ko |
dc.contributor.author | Kim, In Su | ko |
dc.date.accessioned | 2020-12-31T02:10:04Z | - |
dc.date.available | 2020-12-31T02:10:04Z | - |
dc.date.created | 2020-12-29 | - |
dc.date.created | 2020-12-29 | - |
dc.date.created | 2020-12-29 | - |
dc.date.issued | 2020-11 | - |
dc.identifier.citation | ORGANIC LETTERS, v.22, no.22, pp.9004 - 9009 | - |
dc.identifier.issn | 1523-7060 | - |
dc.identifier.uri | http://hdl.handle.net/10203/279373 | - |
dc.description.abstract | A redox-neutral C2-selective methylation of heterocyclic N-oxides with sulfonium ylides is described herein. This report presents unprecedented findings for the utility of sulfonium ylides as the methylation source of N-heterocycles beyond the Corey–Chaykovsky reaction. Intriguingly, pyrrolidine plays a significant role in minimizing the reductive C2-methylation process. This method is characterized by its mild conditions, simplicity, and excellent site selectivity. The applicability of the developed protocol is showcased by the late-stage methylation and sequential transformations of complex drug molecules. | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | C2-Selective C-H Methylation of Heterocyclic N-Oxides with Sulfonium Ylides | - |
dc.type | Article | - |
dc.identifier.wosid | 000592988800049 | - |
dc.identifier.scopusid | 2-s2.0-85096508601 | - |
dc.type.rims | ART | - |
dc.citation.volume | 22 | - |
dc.citation.issue | 22 | - |
dc.citation.beginningpage | 9004 | - |
dc.citation.endingpage | 9009 | - |
dc.citation.publicationname | ORGANIC LETTERS | - |
dc.identifier.doi | 10.1021/acs.orglett.0c03403 | - |
dc.contributor.localauthor | Hong, Sungwoo | - |
dc.contributor.nonIdAuthor | An, Won | - |
dc.contributor.nonIdAuthor | Choi, Su Bin | - |
dc.contributor.nonIdAuthor | Kwon, Na Yeon | - |
dc.contributor.nonIdAuthor | Ghosh, Prithwish | - |
dc.contributor.nonIdAuthor | Han, Sang Hoon | - |
dc.contributor.nonIdAuthor | Mishra, Neeraj Kumar | - |
dc.contributor.nonIdAuthor | Han, Sangil | - |
dc.contributor.nonIdAuthor | Kim, In Su | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
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