Fabrication of non-toxic active ingredients in sunscreen by electron beam irradiation on polymer nanoparticles전자빔 조사를 이용한 무독성 자외선 차단제 유효성분 제조

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dc.contributor.advisorCho, Sung Oh-
dc.contributor.advisor조성오-
dc.contributor.authorLee, Sang Yoon-
dc.date.accessioned2019-09-03T02:48:06Z-
dc.date.available2019-09-03T02:48:06Z-
dc.date.issued2019-
dc.identifier.urihttp://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=843342&flag=dissertationen_US
dc.identifier.urihttp://hdl.handle.net/10203/266592-
dc.description학위논문(석사) - 한국과학기술원 : 원자력및양자공학과, 2019.2,[iv, 37 p. :]-
dc.description.abstractElectron irradiated poly(methyl methacrylate) (PMMA) and polystyrene (PS) nanoparticles as alternatives to existing sunscreen active ingredients which have safety controversies have been studied. The electron irradiation produces chromophores so that the irradiated polymers turn capable of absorbing ultraviolet (UV) rays. UV-Vis spectroscopy indicates a significant increase in the absorbance in the spectral range of UV and a redshift of the absorption edge is observed at a higher electron fluence. Results of FTIR and Raman studies imply chemical alterations of the irradiated polymers, elucidating the creation of UV absorbing properties. According to results of in vitro 3T3 neutral red uptake (NRU) phototoxicity test in compliance with OECD TG 432, the irradiated PMMA was classified as a non-phototoxic material. In addition, in vitro sun protection factors (SPFs) of formulations containing irradiated polymer nanoparticles in various electron fluence were determined according to ISO 24443. In this study, the effects of electron irradiation and the characteristics of the irradiated polymers are discussed.-
dc.languageeng-
dc.publisher한국과학기술원-
dc.subjectElectron irradiation▼aPoly(methyl methacrylate)(PMMA)▼aPolystyrene (PS)▼ananoparticle▼a3T3 NRU PT▼aSun protection factor (SPF)-
dc.subject전자 조사▼a폴리메타크릴산 메틸▼a폴리스타이렌▼a나노 입자▼a광 독성 평가▼a자외선 차단 지수-
dc.titleFabrication of non-toxic active ingredients in sunscreen by electron beam irradiation on polymer nanoparticles-
dc.title.alternative전자빔 조사를 이용한 무독성 자외선 차단제 유효성분 제조-
dc.typeThesis(Master)-
dc.identifier.CNRN325007-
dc.description.department한국과학기술원 :원자력및양자공학과,-
dc.contributor.alternativeauthor이상윤-
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NE-Theses_Master(석사논문)
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