DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Kim, Pilnam | - |
dc.contributor.advisor | 김필남 | - |
dc.contributor.author | Cha, Junghwa | - |
dc.date.accessioned | 2019-08-22T02:41:51Z | - |
dc.date.available | 2019-08-22T02:41:51Z | - |
dc.date.issued | 2018 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=867894&flag=dissertation | en_US |
dc.identifier.uri | http://hdl.handle.net/10203/264680 | - |
dc.description | 학위논문(박사) - 한국과학기술원 : 바이오및뇌공학과, 2018.2,[xix, 210 p. :] | - |
dc.description.abstract | In this research, development of bioengineered biomimetic scaffolds is suggested for studying microenvironment and treatment as an active treatment for glioblastoma multiforme (GBM). Glioblastoma multiforme (GBM) is the most devastating cancer with high mortality, showing remarkable infiltration. Due to the remaining infiltrated GBM cells, current therapeutic approaches are still insufficient to reduce the high death rate of GBM patients, thus a novel treatment is acutely needed to be developed. In part I, the microenvironment models for GBM are suggested to identify the pro-invasive factors and find a new targeted therapy. In part II, a post-surgical, tumor adhesive filling material is suggested as a new, active therapeutic strategies for GBM treatment. Bioengineered scaffolds-based developments could contribute to improvement of survival rates in GBM patients. | - |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.subject | Glioblastoma multiforme▼acancer therapy▼atumor microenvironment▼abioengineered scaffolds▼abiomimetics▼aanti-invasion therapy | - |
dc.subject | 악성뇌종양▼a종양 치료▼a종양 미세환경▼a생체공학 스캐폴드▼a생체 모방▼a침윤 억제 기술 | - |
dc.title | Bioengineered biomimetic scaffolds for studying microenvironment and treatment of malignant glioma | - |
dc.title.alternative | 악성뇌종양-미세환경 모델을 활용한 암세포 침윤 억제 치료기술에 관한 연구 | - |
dc.type | Thesis(Ph.D) | - |
dc.identifier.CNRN | 325007 | - |
dc.description.department | 한국과학기술원 :바이오및뇌공학과, | - |
dc.contributor.alternativeauthor | 차정화 | - |
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