Polypeptide for binding to complement protein C5A, and use of same보체 단백질 C5a와 결합할 수 있는 신규한 폴리펩타이드 및 그 용도
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kim, Hak-Sung | ko |
| dc.contributor.author | Hwang, Da Eun | ko |
| dc.contributor.author | Choi, Jung-Min | ko |
| dc.contributor.author | Lee, Joong-Jae | ko |
| dc.contributor.author | Heu, Woosung | ko |
| dc.date.accessioned | 2019-06-04T06:25:13Z | - |
| dc.date.available | 2019-06-04T06:25:13Z | - |
| dc.date.issued | 2019-05-14 | - |
| dc.identifier.uri | http://hdl.handle.net/10203/262462 | - |
| dc.description.abstract | The present invention relates to novel polypeptide for binding to a complement protein C5a. More particularly, the present invention relates to polypeptide which can be bound to a complement protein C5a and inhibit the activation of same, polynucleotide which codes for the polypeptide, a recombinant vector which comprises the polynucleotide, a recombinant microorganism to which the recombinant vector has been introduced, a method for producing the polypeptide by means of the recombinant microorganism, and a pharmaceutical composition, for treating immune diseases or sepsis, containing the polypeptide. A polypeptide, according to the present invention, can be bound to a complement protein C5a, with higher affinity compared to being bound to a complement protein C5a receptor which is present in nature, and inhibits the activation of same, thus being widely utilized for development of formulation for preventing or treating diseases related to a complement protein C5a. | - |
| dc.title | Polypeptide for binding to complement protein C5A, and use of same | - |
| dc.title.alternative | 보체 단백질 C5a와 결합할 수 있는 신규한 폴리펩타이드 및 그 용도 | - |
| dc.type | Patent | - |
| dc.type.rims | PAT | - |
| dc.contributor.localauthor | Kim, Hak-Sung | - |
| dc.contributor.nonIdAuthor | Hwang, Da Eun | - |
| dc.contributor.nonIdAuthor | Choi, Jung-Min | - |
| dc.contributor.nonIdAuthor | Lee, Joong-Jae | - |
| dc.contributor.nonIdAuthor | Heu, Woosung | - |
| dc.contributor.assignee | KAIST | - |
| dc.identifier.iprsType | 특허 | - |
| dc.identifier.patentApplicationNumber | 15500921 | - |
| dc.identifier.patentRegistrationNumber | 10287342 | - |
| dc.date.application | 2015-08-03 | - |
| dc.date.registration | 2019-05-14 | - |
| dc.publisher.country | US | - |
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