DC Field | Value | Language |
---|---|---|
dc.contributor.author | Eun, Hyunmin | ko |
dc.contributor.author | Kwon, Woo Young | ko |
dc.contributor.author | Kalimuthu, Kalishwaralal | ko |
dc.contributor.author | Kim, Yonghwan | ko |
dc.contributor.author | Lee, Miran | ko |
dc.contributor.author | Ahn, Jung-Oh | ko |
dc.contributor.author | Lee, Hongweon | ko |
dc.contributor.author | Lee, Sang Hyun | ko |
dc.contributor.author | Kim, Hyung Joo | ko |
dc.contributor.author | Park, Hyun Gyu | ko |
dc.contributor.author | Park, Ki Soo | ko |
dc.date.accessioned | 2019-05-15T13:25:44Z | - |
dc.date.available | 2019-05-15T13:25:44Z | - |
dc.date.created | 2019-05-13 | - |
dc.date.created | 2019-05-13 | - |
dc.date.created | 2019-05-13 | - |
dc.date.issued | 2019-04 | - |
dc.identifier.citation | JOURNAL OF MATERIALS CHEMISTRY B, v.7, no.15, pp.2512 - 2517 | - |
dc.identifier.issn | 2050-750X | - |
dc.identifier.uri | http://hdl.handle.net/10203/261867 | - |
dc.description.abstract | A new method has been developed for the preparation of brightly fluorescent and stable DNA-silver nanoclusters (DNA-AgNCs). The approach takes advantage of specific interactions occurring between melamine and thymine residues in a DNA template. These interactions cause the formation of a melamine-DNA-AgNC complex (Mel-DNA-AgNCs), in which a change in the environment of the DNA template causes binding of additional Ag+ and an enhancement in the fluorescence efficiency and stability. The effects of the nature of the template DNA, DNA:Ag+:NaBH4 ratio, pH and temperature were systematically assessed in order to maximize the melamine-promoted fluorescence enhancement. The results show that the Mel-DNA-AgNCs, generated under the optimal conditions, exhibit a ca. 3-fold larger fluorescence efficiency and long-term stability (70 d) in contrast to those of DNA-AgNCs in the absence of melamine. Importantly, the bright and stable Mel-DNA-AgNCs exhibit antimicrobial activities against Gram-positive and Gram-negative bacteria that are superior to those of DNA-AgNCs alone. To the best of our knowledge, this is the first report describing the synthesis of DNA-AgNCs that have improved fluorescence efficiencies and that function as effective antimicrobial agents. | - |
dc.language | English | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Melamine-promoted formation of bright and stable DNA-silver nanoclusters and their antimicrobial properties | - |
dc.type | Article | - |
dc.identifier.wosid | 000465281100010 | - |
dc.identifier.scopusid | 2-s2.0-85064155383 | - |
dc.type.rims | ART | - |
dc.citation.volume | 7 | - |
dc.citation.issue | 15 | - |
dc.citation.beginningpage | 2512 | - |
dc.citation.endingpage | 2517 | - |
dc.citation.publicationname | JOURNAL OF MATERIALS CHEMISTRY B | - |
dc.identifier.doi | 10.1039/c8tb03166e | - |
dc.contributor.localauthor | Park, Hyun Gyu | - |
dc.contributor.nonIdAuthor | Eun, Hyunmin | - |
dc.contributor.nonIdAuthor | Kwon, Woo Young | - |
dc.contributor.nonIdAuthor | Kalimuthu, Kalishwaralal | - |
dc.contributor.nonIdAuthor | Kim, Yonghwan | - |
dc.contributor.nonIdAuthor | Lee, Miran | - |
dc.contributor.nonIdAuthor | Ahn, Jung-Oh | - |
dc.contributor.nonIdAuthor | Lee, Hongweon | - |
dc.contributor.nonIdAuthor | Lee, Sang Hyun | - |
dc.contributor.nonIdAuthor | Kim, Hyung Joo | - |
dc.contributor.nonIdAuthor | Park, Ki Soo | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | ANTIBACTERIAL ACTIVITY | - |
dc.subject.keywordPlus | FLUORESCENT | - |
dc.subject.keywordPlus | ION | - |
dc.subject.keywordPlus | ASSAY | - |
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