Emerging tools for synthetic genome design

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dc.contributor.authorLee, Bo-Rahmko
dc.contributor.authorCho, Suhyungko
dc.contributor.authorSong, Yosebko
dc.contributor.authorKim, Sun-Changko
dc.contributor.authorCho, Byung-Kwanko
dc.date.accessioned2019-04-15T15:31:13Z-
dc.date.available2019-04-15T15:31:13Z-
dc.date.created2013-06-12-
dc.date.issued2013-05-
dc.identifier.citationMOLECULES AND CELLS, v.35, no.5, pp.359 - 370-
dc.identifier.issn1016-8478-
dc.identifier.urihttp://hdl.handle.net/10203/255022-
dc.description.abstractSynthetic biology is an emerging discipline for designing and synthesizing predictable, measurable, controllable, and transformable biological systems. These newly designed biological systems have great potential for the development of cheaper drugs, green fuels, biodegradable plastics, and targeted cancer therapies over the coming years. Fortunately, our ability to quickly and accurately engineer biological systems that behave predictably has been dramatically expanded by significant advances in DNA-sequencing, DNA-synthesis, and DNA-editing technologies. Here, we review emerging technologies and methodologies in the field of building designed biological systems, and we discuss their future perspectives.-
dc.languageEnglish-
dc.publisherKOREAN SOC MOLECULAR CELLULAR BIOLOGY-
dc.subjectZINC-FINGER NUCLEASES-
dc.subjectTARGETED GENE DISRUPTION-
dc.subjectPROTEIN-DNA INTERACTIONS-
dc.subjectESCHERICHIA-COLI GENOME-
dc.subjectCRISPR-CAS SYSTEMS-
dc.subjectSINGLE-NUCLEOTIDE RESOLUTION-
dc.subjectSTRAND BREAK REPAIR-
dc.subjectRNA-SEQ DATA-
dc.subjectHOMOLOGOUS RECOMBINATION-
dc.subjectCHIP-SEQ-
dc.titleEmerging tools for synthetic genome design-
dc.typeArticle-
dc.identifier.wosid000319473800001-
dc.identifier.scopusid2-s2.0-84879074498-
dc.type.rimsART-
dc.citation.volume35-
dc.citation.issue5-
dc.citation.beginningpage359-
dc.citation.endingpage370-
dc.citation.publicationnameMOLECULES AND CELLS-
dc.identifier.doi10.1007/s10059-013-0127-5-
dc.contributor.localauthorKim, Sun-Chang-
dc.contributor.localauthorCho, Byung-Kwan-
dc.contributor.nonIdAuthorLee, Bo-Rahm-
dc.contributor.nonIdAuthorCho, Suhyung-
dc.contributor.nonIdAuthorSong, Yoseb-
dc.type.journalArticleReview-
dc.subject.keywordAuthorgenome-
dc.subject.keywordAuthorgenome editing-
dc.subject.keywordAuthornext-generation sequencing-
dc.subject.keywordAuthorsynthetic biology-
dc.subject.keywordPlusZINC-FINGER NUCLEASES-
dc.subject.keywordPlusTARGETED GENE DISRUPTION-
dc.subject.keywordPlusPROTEIN-DNA INTERACTIONS-
dc.subject.keywordPlusESCHERICHIA-COLI GENOME-
dc.subject.keywordPlusCRISPR-CAS SYSTEMS-
dc.subject.keywordPlusSINGLE-NUCLEOTIDE RESOLUTION-
dc.subject.keywordPlusSTRAND BREAK REPAIR-
dc.subject.keywordPlusRNA-SEQ DATA-
dc.subject.keywordPlusHOMOLOGOUS RECOMBINATION-
dc.subject.keywordPlusCLONING METHOD-
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