DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Jae Yoon | ko |
dc.contributor.author | Kim, Jee Seon | ko |
dc.contributor.author | Nam, YoonSung | ko |
dc.date.accessioned | 2019-04-15T15:10:04Z | - |
dc.date.available | 2019-04-15T15:10:04Z | - |
dc.date.created | 2013-09-30 | - |
dc.date.issued | 2013-09 | - |
dc.identifier.citation | CARBOHYDRATE POLYMERS, v.97, no.2, pp.753 - 757 | - |
dc.identifier.issn | 0144-8617 | - |
dc.identifier.uri | http://hdl.handle.net/10203/254696 | - |
dc.description.abstract | Surface modification of inorganic materials to prevent non-specific protein adsorption is critically important for developing a biocompatible materials' platform for medical implantation, diagnostics, and therapeutics. Here we report mussel-inspired chemical modification of dextran for anti-fouling coatings of metal oxide. Catechols are conjugated to dextran via a carbamate ester linkage, producing catechol-grafted dextran with a grafting density of 7.3 mol.%. Titanium dioxide (TiO2) is coated with the catechol-grafted dextran, and the anti-fouling effect of dextran coatings is examined by using the adsorption of human serum albumin. The mussel-inspired dextran coatings show excellent resistance to non-specific protein adsorption: the adsorption equilibrium constant (K) is 0.69 Lg(-1) for dextran-coated TiO2 while that for pristine TiO2 surface is 3.53 Lg(-1). This study suggests that catechol-grafted dextran is a promising material for effective anti-fouling coatings of implantable inorganic materials. (C) 2013 Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.subject | IN-VITRO | - |
dc.subject | POLY(ETHYLENE GLYCOL) | - |
dc.subject | METALLIC BIOMATERIALS | - |
dc.subject | SURFACTANT POLYMERS | - |
dc.subject | PLATELET-ADHESION | - |
dc.subject | ADSORPTION | - |
dc.subject | IMPLANTS | - |
dc.subject | RELEASE | - |
dc.subject | NANOPARTICLES | - |
dc.subject | PEGYLATION | - |
dc.title | Mussel-inspired modification of dextran for protein-resistant coatings of titanium oxide | - |
dc.type | Article | - |
dc.identifier.wosid | 000323805000069 | - |
dc.identifier.scopusid | 2-s2.0-84879199207 | - |
dc.type.rims | ART | - |
dc.citation.volume | 97 | - |
dc.citation.issue | 2 | - |
dc.citation.beginningpage | 753 | - |
dc.citation.endingpage | 757 | - |
dc.citation.publicationname | CARBOHYDRATE POLYMERS | - |
dc.identifier.doi | 10.1016/j.carbpol.2013.05.064 | - |
dc.contributor.localauthor | Nam, YoonSung | - |
dc.contributor.nonIdAuthor | Park, Jae Yoon | - |
dc.contributor.nonIdAuthor | Kim, Jee Seon | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Anti-fouling | - |
dc.subject.keywordAuthor | Dextran | - |
dc.subject.keywordAuthor | Catechol | - |
dc.subject.keywordAuthor | Protein adsorption | - |
dc.subject.keywordAuthor | Titanium dioxide | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | POLY(ETHYLENE GLYCOL) | - |
dc.subject.keywordPlus | METALLIC BIOMATERIALS | - |
dc.subject.keywordPlus | SURFACTANT POLYMERS | - |
dc.subject.keywordPlus | PLATELET-ADHESION | - |
dc.subject.keywordPlus | ADSORPTION | - |
dc.subject.keywordPlus | IMPLANTS | - |
dc.subject.keywordPlus | RELEASE | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | PEGYLATION | - |
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