Effect of preparation and reaction condition on the catalytic performance of Mo-V-Te-Nb catalysts for selective oxidation of propane to acrylic acid by high-throughput methodology

Abstract

Combinatorial screening technique has been applied to investigate the catalytic activity and selectivity of quaternary Mo-V-Te-Nb mixed oxide catalysts treated with various chemicals during preparation for selective oxidation of propane to acrylic acid. The catalyst libraries were prepared by the slurry method and catalytic activities were examined in 32-channel high-throughput screening reactor system coupled with a mass spectrometer and/or gas chromatograph. The obtained results provided substantial evidence that the sample preparation condition would have strong effect on the catalytic performance for propane selective oxidation. Among screened samples, Mo-V-Te-Nb treated with HIO(3) solution presented a better performance. The reaction results of promising catalysts selected from the libraries were applied to further scale-up of the system and confirmed catalytic performance. Quantification of the result of Mo-V-Te-Nb treated with HIO(3) solution was realized by combination of CC and MS and relationship between the MS data and the CC results can be established. (C) 2008 Elsevier B.V. All rights reserved.