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College of Engineering(공과대학)Dept. of Chemical and Biomolecular Engineering(생명화학공학과)CBE-Journal Papers(저널논문)

Polymer-coated spherical mesoporous silica for pH-controlled delivery of insulin

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dc.contributor.authorChoi, Sae Romko
dc.contributor.authorJang, Dong-Jinko
dc.contributor.authorKim, Sanghyunko
dc.contributor.authorAn, Sunhyungko
dc.contributor.authorLee, Jinwooko
dc.contributor.authorOh, Euichaulko
dc.contributor.authorKim, Jungbaeko
dc.date.accessioned2018-08-20T08:23:59Z-
dc.date.available2018-08-20T08:23:59Z-
dc.date.created2018-08-08-
dc.date.created2018-08-08-
dc.date.issued2014-
dc.identifier.citationJOURNAL OF MATERIALS CHEMISTRY B, v.2, no.6, pp.616 - 619-
dc.identifier.issn2050-750X-
dc.identifier.urihttp://hdl.handle.net/10203/245063-
dc.description.abstractWe report a pH-controlled insulin release system to provide an oral administration route. Mesoporous silica was chosen as a drug carrier, and pH-sensitive polymers were coated onto spherical mesocellular foam with pre-adsorbed insulin. We evaluated the insulin release in both acidic and neutral solutions to compare how this systembehaves under different pH conditions.-
dc.languageEnglish-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectDRUG-DELIVERY-
dc.subjectORAL DELIVERY-
dc.subjectIN-VITRO-
dc.subjectNANOPARTICLES-
dc.subjectRELEASE-
dc.subjectCHALLENGES-
dc.subjectSTABILITY-
dc.subjectMATRICES-
dc.subjectSYSTEMS-
dc.subjectPROTEIN-
dc.titlePolymer-coated spherical mesoporous silica for pH-controlled delivery of insulin-
dc.typeArticle-
dc.identifier.wosid000329936400002-
dc.identifier.scopusid2-s2.0-84892568449-
dc.type.rimsART-
dc.citation.volume2-
dc.citation.issue6-
dc.citation.beginningpage616-
dc.citation.endingpage619-
dc.citation.publicationnameJOURNAL OF MATERIALS CHEMISTRY B-
dc.identifier.doi10.1039/c3tb21494j-
dc.contributor.localauthorLee, Jinwoo-
dc.contributor.nonIdAuthorChoi, Sae Rom-
dc.contributor.nonIdAuthorJang, Dong-Jin-
dc.contributor.nonIdAuthorKim, Sanghyun-
dc.contributor.nonIdAuthorAn, Sunhyung-
dc.contributor.nonIdAuthorOh, Euichaul-
dc.contributor.nonIdAuthorKim, Jungbae-
dc.description.isOpenAccessN-
dc.type.journalArticleArticle-
dc.subject.keywordPlusDRUG-DELIVERY-
dc.subject.keywordPlusORAL DELIVERY-
dc.subject.keywordPlusIN-VITRO-
dc.subject.keywordPlusNANOPARTICLES-
dc.subject.keywordPlusRELEASE-
dc.subject.keywordPlusCHALLENGES-
dc.subject.keywordPlusSTABILITY-
dc.subject.keywordPlusMATRICES-
dc.subject.keywordPlusSYSTEMS-
dc.subject.keywordPlusPROTEIN-
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