Genetic incorporation of L-dihydroxyphenylalanine (DOPA) biosynthesized by a tyrosine phenol-lyase

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dc.contributor.authorKim, Sanggilko
dc.contributor.authorSung, Bong Hyunko
dc.contributor.authorKim, Sun Changko
dc.contributor.authorLee, Hyun Sooko
dc.date.accessioned2018-04-24T05:07:39Z-
dc.date.available2018-04-24T05:07:39Z-
dc.date.created2018-04-09-
dc.date.created2018-04-09-
dc.date.issued2018-03-
dc.identifier.citationCHEMICAL COMMUNICATIONS, v.54, no.24, pp.3002 - 3005-
dc.identifier.issn1359-7345-
dc.identifier.urihttp://hdl.handle.net/10203/241321-
dc.description.abstractL-Dihydroxyphenylalanine (DOPA) was biosynthesized by a tyrosine-phenol lyase from catechol, pyruvate, and ammonia in Escherichia coli, and the biosynthesized amino acid was directly incorporated into proteins. Three biochemical experiments with mutant proteins containing DOPA confirmed the genetic incorporation of biosynthesized DOPA, and revealed its potential for various biochemical applications.-
dc.languageEnglish-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectUNNATURAL AMINO-ACIDS-
dc.subjectTRANSFER-RNA SYNTHETASES-
dc.subjectPROTEIN CROSS-LINKING-
dc.subjectESCHERICHIA-COLI-
dc.subjectSTRUCTURAL BASIS-
dc.subjectCODE-
dc.subjectEVOLUTION-
dc.subject3,4-DIHYDROXYPHENYL-L-ALANINE-
dc.subjectCONJUGATION-
dc.titleGenetic incorporation of L-dihydroxyphenylalanine (DOPA) biosynthesized by a tyrosine phenol-lyase-
dc.typeArticle-
dc.identifier.wosid000428086500012-
dc.identifier.scopusid2-s2.0-85044226860-
dc.type.rimsART-
dc.citation.volume54-
dc.citation.issue24-
dc.citation.beginningpage3002-
dc.citation.endingpage3005-
dc.citation.publicationnameCHEMICAL COMMUNICATIONS-
dc.identifier.doi10.1039/c8cc00281a-
dc.contributor.localauthorKim, Sun Chang-
dc.contributor.nonIdAuthorKim, Sanggil-
dc.contributor.nonIdAuthorSung, Bong Hyun-
dc.contributor.nonIdAuthorLee, Hyun Soo-
dc.description.isOpenAccessN-
dc.type.journalArticleArticle-
dc.subject.keywordPlusUNNATURAL AMINO-ACIDS-
dc.subject.keywordPlusTRANSFER-RNA SYNTHETASES-
dc.subject.keywordPlusPROTEIN CROSS-LINKING-
dc.subject.keywordPlusESCHERICHIA-COLI-
dc.subject.keywordPlusSTRUCTURAL BASIS-
dc.subject.keywordPlusCODE-
dc.subject.keywordPlusEVOLUTION-
dc.subject.keywordPlus3,4-DIHYDROXYPHENYL-L-ALANINE-
dc.subject.keywordPlusCONJUGATION-
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