DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hilderbrand, SA | ko |
dc.contributor.author | Lim, Mi Hee | ko |
dc.contributor.author | Lippard, SJ | ko |
dc.date.accessioned | 2018-02-21T06:25:39Z | - |
dc.date.available | 2018-02-21T06:25:39Z | - |
dc.date.created | 2018-02-08 | - |
dc.date.created | 2018-02-08 | - |
dc.date.created | 2018-02-08 | - |
dc.date.issued | 2004-04 | - |
dc.identifier.citation | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.126, no.15, pp.4972 - 4978 | - |
dc.identifier.issn | 0002-7863 | - |
dc.identifier.uri | http://hdl.handle.net/10203/240339 | - |
dc.description.abstract | We report the synthesis and characterization of dirhodium tetracarboxylate complexes [Rh-2(mu-O2CR)(4)(L)(2)], with R = Me and L = dansyl-imidazole (Ds-im) or dansyl-piperazine (Ds-pip). The fluorophores coordinate to the axial sites of the dirhodium core through the imidazole or piperazine N-atom and emit only weakly when excited at 365 or 345 nm for the Ds-im and Ds-pip complexes, respectively. These fluorophore-containing complexes were investigated for their ability to elicit a fluorescence response in the presence of NO. An immediate increase in fluorescence emission of greater than 15-fold occurs when NO is admitted to solutions containing [Rh-2(mu-O2CMe)(4)] and Ds-pip or Ds-im. In both systems, the fluorescence response, which arises by NO-induced displacement of the axially coordinated fluorophore, is reversible with a sensitivity of similar to4 muM. The related dinitrosyl complexes [Rh-2(mu-O2CR)(4)(NO)(2)], where R = Me, Et, or n-Pr, were prepared, structurally characterized, and found to be air-stable, losing NO upon standing in solution. Sequestration of a methylene chloride solution of the Ds-pip complex from aqueous media by a NO-permeable membrane allows for fluorescence detection of NO for potential applications in biological fluids. | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors | - |
dc.type | Article | - |
dc.identifier.wosid | 000220849900047 | - |
dc.identifier.scopusid | 2-s2.0-1842841021 | - |
dc.type.rims | ART | - |
dc.citation.volume | 126 | - |
dc.citation.issue | 15 | - |
dc.citation.beginningpage | 4972 | - |
dc.citation.endingpage | 4978 | - |
dc.citation.publicationname | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | - |
dc.identifier.doi | 10.1021/ja038471j | - |
dc.contributor.localauthor | Lim, Mi Hee | - |
dc.contributor.nonIdAuthor | Hilderbrand, SA | - |
dc.contributor.nonIdAuthor | Lippard, SJ | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | LONG-TERM POTENTIATION | - |
dc.subject.keywordPlus | BIOLOGICAL-SYSTEMS | - |
dc.subject.keywordPlus | CRYSTAL-STRUCTURES | - |
dc.subject.keywordPlus | NITROGEN MONOXIDE | - |
dc.subject.keywordPlus | NOBEL LECTURE | - |
dc.subject.keywordPlus | NO | - |
dc.subject.keywordPlus | LIGANDS | - |
dc.subject.keywordPlus | REACTIVITY | - |
dc.subject.keywordPlus | BIOSENSORS | - |
dc.subject.keywordPlus | COMPLEXES | - |
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