DC Field | Value | Language |
---|---|---|
dc.contributor.author | Braymer, Joseph J. | ko |
dc.contributor.author | Merrill, Nathan M. | ko |
dc.contributor.author | Lim, Mi Hee | ko |
dc.date.accessioned | 2018-02-21T06:24:57Z | - |
dc.date.available | 2018-02-21T06:24:57Z | - |
dc.date.created | 2018-02-08 | - |
dc.date.created | 2018-02-08 | - |
dc.date.created | 2018-02-08 | - |
dc.date.issued | 2012-01 | - |
dc.identifier.citation | INORGANICA CHIMICA ACTA, v.380, pp.261 - 268 | - |
dc.identifier.issn | 0020-1693 | - |
dc.identifier.uri | http://hdl.handle.net/10203/240311 | - |
dc.description.abstract | Bidentate pyridinylimine (L1-a and L1-b) and pyridinylmethylamine (L2-a and L2-b) derivatives have recently received attention due to their potential use as chemical reagants that can target metal-associated amyloid-beta (A beta) species and modulate metal-induced A beta aggregation and neurotoxicity in vitro and in living cells. Herein, we report the characterization of these bidentate ligands and their corresponding metal complexes by X-ray crystallography and spectroscopic methods, including UV-Vis spectroscopy (UV-Vis), nuclear magnetic resonance spectroscopy (NMR), and Fourier transform infrared spectroscopy (FT-IR). Our studies presented how the different structural moieties of ligand frameworks (L1-a, L1-b, L2-a, and L2-b), in addition to effects of metal binding, contribute to variations in structure and chemical environments of the ligands and their corresponding metal complexes. (C) 2011 Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCIENCE SA | - |
dc.title | Characterization of pyridinylimine and pyridinylmethylamine derivatives and their corresponding metal complexese | - |
dc.type | Article | - |
dc.identifier.wosid | 000300180100035 | - |
dc.identifier.scopusid | 2-s2.0-84856232089 | - |
dc.type.rims | ART | - |
dc.citation.volume | 380 | - |
dc.citation.beginningpage | 261 | - |
dc.citation.endingpage | 268 | - |
dc.citation.publicationname | INORGANICA CHIMICA ACTA | - |
dc.identifier.doi | 10.1016/j.ica.2011.08.056 | - |
dc.contributor.localauthor | Lim, Mi Hee | - |
dc.contributor.nonIdAuthor | Braymer, Joseph J. | - |
dc.contributor.nonIdAuthor | Merrill, Nathan M. | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Bioinorganic chemistry | - |
dc.subject.keywordAuthor | Metal complexes of pyridinylimine and pyridinylmethylamine derivatives | - |
dc.subject.keywordAuthor | Spectroscopic studies | - |
dc.subject.keywordAuthor | X-ray crystal structure determination | - |
dc.subject.keywordPlus | BETA-AMYLOID PLAQUES | - |
dc.subject.keywordPlus | ALZHEIMERS-DISEASE | - |
dc.subject.keywordPlus | TRANSGENIC MICE | - |
dc.subject.keywordPlus | A-BETA | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | DESIGN | - |
dc.subject.keywordPlus | LIGAND | - |
dc.subject.keywordPlus | ACCUMULATION | - |
dc.subject.keywordPlus | STABILITY | - |
dc.subject.keywordPlus | QUINOLINE | - |
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