Apart from applications in mechanical engineering, now even the domain of medicine may benefit from the
option of using metallic materials for Direct Manufacturing. In the medical domain, the use of biocompatible
materials, such as titanium or titanium alloys is essential to produce individual implants. As a result of this
development, it is now possible to generate new patient-specific geometries fitted to the contour. This paper
elucidates the process chain to derive individual design variants and to produce patient-specific bone
replacement implants for the lower jaw-bone regions by using innovative reverse engineering and
manufacturing methods. For this interdisciplinary project, technical scientists, medical scientists at the
university hospital and engineers from a product development firm work together.