세포 환경 내에서의 단일 분자 수준의 단백질-단백질 상호작용 분석 방법On single molecules level in cellular environment the method and apparatus of analyzing proteins-protein-interacting

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The invention discloses a kind of method and apparatus of analyzing proteins protein-interacting on single molecules level.The present invention is realized by the method for following steps: provide the first albumen in the first substrate, over the substrate, the first mark combination on biological molecular sieve and the first albumen, thus induce the combination that first on biological molecular sieve and the first albumen mark;After biological molecular sieve and the first mark combine, it is provided that the cytosol of the cell containing second mark the second albumen is in this substrate;While cytosol is supplied to described substrate, analyze the interaction between the first albumen and the second albumen.By the method for the present invention, even can interaction between analyzing proteins albumen on single molecules level in the actual environment of cell.
Assignee
KAIST
Country
CC (Cocos (Keeling) Islands)
Issue Date
2016-09-07
Application Date
2012-04-20
Application Number
201280026166
Registration Date
2016-09-07
Registration Number
103608677
URI
http://hdl.handle.net/10203/230031
Appears in Collection
PH-Patent(특허)
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