DC Field | Value | Language |
---|---|---|
dc.contributor.author | Koh, Hyongjong | ko |
dc.contributor.author | Chung, Jongkyeong | ko |
dc.date.accessioned | 2007-12-03T02:02:56Z | - |
dc.date.available | 2007-12-03T02:02:56Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2007-11 | - |
dc.identifier.citation | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.362, no.4, pp.789 - 792 | - |
dc.identifier.issn | 0006-291X | - |
dc.identifier.uri | http://hdl.handle.net/10203/2257 | - |
dc.description.abstract | AMP-activated protein kinase (AMPK) is known as an important cellular energy sensor, but its in vivo role has not been fully understood. Recent studies provided surprising results that AMPK regulates cell polarity and mitosis under the control of tumour suppressor LKB1. Moreover, these newly found in vivo functions of AMPK are regulated by energy status in a cell autonomous manner. These findings provide novel insights into the physiological function of AMPK and the treatment of AMPK-related diseases such as cancer and diabetes. (c) 2007 Elsevier Inc. All rights reserved. | - |
dc.description.sponsorship | We thank Yongsung Kim and Jeehye Park for helpful discussions and critical reading of the manuscript. The work was supported by a National Creative Research Initiatives Grant (R16-2001-002-01001-0) from the Korean Ministry of Science and Technology/KOSEF. | en |
dc.language | English | - |
dc.language.iso | en_US | en |
dc.publisher | ACADEMIC PRESS INC ELSEVIER SCIENCE | - |
dc.subject | ACTIVATED PROTEIN-KINASE | - |
dc.subject | SERINE-THREONINE KINASE | - |
dc.subject | HAPLOID INVASIVE GROWTH | - |
dc.subject | PEUTZ-JEGHERS-SYNDROME | - |
dc.subject | C-ELEGANS | - |
dc.subject | MYOSIN-II | - |
dc.subject | DROSOPHILA-MELANOGASTER | - |
dc.subject | NONMUSCLE MYOSIN | - |
dc.subject | LKB1 KINASE | - |
dc.subject | POLARITY | - |
dc.title | AMPK links energy status to cell structure and mitosis | - |
dc.type | Article | - |
dc.identifier.wosid | 000249798800002 | - |
dc.identifier.scopusid | 2-s2.0-34548553073 | - |
dc.type.rims | ART | - |
dc.citation.volume | 362 | - |
dc.citation.issue | 4 | - |
dc.citation.beginningpage | 789 | - |
dc.citation.endingpage | 792 | - |
dc.citation.publicationname | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | - |
dc.identifier.doi | 10.1016/j.bbrc.2007.08.016 | - |
dc.embargo.liftdate | 9999-12-31 | - |
dc.embargo.terms | 9999-12-31 | - |
dc.contributor.localauthor | Chung, Jongkyeong | - |
dc.contributor.nonIdAuthor | Koh, Hyongjong | - |
dc.type.journalArticle | Review | - |
dc.subject.keywordAuthor | AMPK | - |
dc.subject.keywordAuthor | LKB1 | - |
dc.subject.keywordAuthor | MRLC | - |
dc.subject.keywordAuthor | MLC2 | - |
dc.subject.keywordAuthor | energy status | - |
dc.subject.keywordAuthor | cell polarity | - |
dc.subject.keywordAuthor | mitosis | - |
dc.subject.keywordPlus | ACTIVATED PROTEIN-KINASE | - |
dc.subject.keywordPlus | SERINE-THREONINE KINASE | - |
dc.subject.keywordPlus | HAPLOID INVASIVE GROWTH | - |
dc.subject.keywordPlus | PEUTZ-JEGHERS-SYNDROME | - |
dc.subject.keywordPlus | C-ELEGANS | - |
dc.subject.keywordPlus | MYOSIN-II | - |
dc.subject.keywordPlus | DROSOPHILA-MELANOGASTER | - |
dc.subject.keywordPlus | NONMUSCLE MYOSIN | - |
dc.subject.keywordPlus | LKB1 KINASE | - |
dc.subject.keywordPlus | POLARITY | - |
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