Multiple-TR Neuronal Resonance-MRI (NR-MRI) for Detection of Weak Oscillating Magnetic Field

Abstract

We propose a new approach termed neuronal resonance MRI (NR-MRI) with multiple TRs for detection of weak oscillating magnetic field. NR MRI could detect signals from oscillating magnetic fields with random frequency, phase, and on/off intervals, without synchronization between MR acquisition and neuronal oscillation. The detected signals showed higher SNR with increasing number of dynamic scans, demonstrating that temporal averaging is possible with NR-MRI. Two‑TR approach showed multiple frequency components in an absolute frequency spectrum with no a priori target frequency information while suppressing the systematic noises, which warrants further investigation.