DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yoo J. | ko |
dc.contributor.author | Kim J.-H. | ko |
dc.contributor.author | Do, Youngkyu | ko |
dc.contributor.author | Sohn Y.S. | ko |
dc.date.accessioned | 2007-11-28T02:09:46Z | - |
dc.date.available | 2007-11-28T02:09:46Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 1997 | - |
dc.identifier.citation | INORGANICA CHIMICA ACTA, v.263, no.2016-01-02, pp.53 - 60 | - |
dc.identifier.issn | 0020-1693 | - |
dc.identifier.uri | http://hdl.handle.net/10203/2204 | - |
dc.description.abstract | The reaction of 3,3'-disubstituted-2,2'-bipyridines, 2,2'-bipyridyl-3,3'-dicarboxylic acid (H2BDC) and 3,3'-dimethylol-2,2'-bipyridine (DMB) with potassium tetrachloroplatinate(II) in water gives Pt(H2BDC)Cl-2 (1) and Pt(DMB)CI, (2), respectively. Both complexes were characterized by elemental analysis and various spectroscopic techniques. The molecular structures of 1 and 2 have been determined by single-crystal X-ray diffraction. 1.2DMF: triclinic system, space groupP1,alpha=8.089(9) Angstrom,b=9.707(8) Angstrom,c= 15.541(4) Angstrom,alpha = 106.88(6)degrees, beta=100.41(3)degrees: gamma=94.39(8)degrees, V=1137.8(2) Angstrom(3), Z=2. 2: monoclinic system, space group P2(1)/c, alpha=7.849(5) Angstrom, b=16.125(3) Angstrom, c=21.613(5) Angstrom, beta=94.10(2)degrees, V= 2728.5(9) Angstrom(3), Z=8. X-ray structures indicate that two pyridine rings of the bipyridyl ligand in both compounds cannot attain the coplanar state owing to the steric bulkiness of the substituents in the 3,3'-positions. The solvolysis of 1 in DMSO, characterized by H-1, C-13 and Pt-195 NMR spectra, leads to the unprecedented example for the complete release of the free amine ligand H2BDC, yielding the formation of cis-[Pt(Me2SO)(2)Cl-2]. No antitumor activity was observed for 1 and 2 against the leukemia L1210 cell line. (C) 1997 Elsevier Science S.A. | - |
dc.description.sponsorship | no sponsors | en |
dc.language | English | - |
dc.language.iso | en_US | en |
dc.publisher | ELSEVIER SCIENCE SA LAUSANNE | - |
dc.subject | DNA-BINDING | - |
dc.subject | CRYSTAL-STRUCTURE | - |
dc.subject | ALPHA-DIIMINE | - |
dc.subject | LIGANDS | - |
dc.subject | CHEMISTRY | - |
dc.title | Platinum(II) complexes of 3,3'-disubstituted-2,2'-bipyridines. Synthesis, structures, cytotoxic effect and unusual solvolysis in DMSO | - |
dc.type | Article | - |
dc.identifier.wosid | A1997YD82100008 | - |
dc.type.rims | ART | - |
dc.citation.volume | 263 | - |
dc.citation.issue | 2016-01-02 | - |
dc.citation.beginningpage | 53 | - |
dc.citation.endingpage | 60 | - |
dc.citation.publicationname | INORGANICA CHIMICA ACTA | - |
dc.identifier.doi | 10.1016/S0020-1693(97)05566-7 | - |
dc.embargo.liftdate | 9999-12-31 | - |
dc.embargo.terms | 9999-12-31 | - |
dc.contributor.localauthor | Do, Youngkyu | - |
dc.contributor.nonIdAuthor | Yoo J. | - |
dc.contributor.nonIdAuthor | Kim J.-H. | - |
dc.contributor.nonIdAuthor | Sohn Y.S. | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | platinum complexes | - |
dc.subject.keywordAuthor | bipyridine complexes | - |
dc.subject.keywordAuthor | anticancer agent | - |
dc.subject.keywordAuthor | solvolysis | - |
dc.subject.keywordAuthor | crystal structures | - |
dc.subject.keywordAuthor | cytotoxicity | - |
dc.subject.keywordPlus | DNA-BINDING | - |
dc.subject.keywordPlus | CRYSTAL-STRUCTURE | - |
dc.subject.keywordPlus | ALPHA-DIIMINE | - |
dc.subject.keywordPlus | LIGANDS | - |
dc.subject.keywordPlus | CHEMISTRY | - |
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