DC Field | Value | Language |
---|---|---|
dc.contributor.author | Nam, Yoon Sung | ko |
dc.contributor.author | Kim, Jin-Woong | ko |
dc.contributor.author | Shim, Jongwon | ko |
dc.contributor.author | Han, Sang Hoon | ko |
dc.contributor.author | Kim, Han Kon | ko |
dc.date.accessioned | 2016-07-06T04:28:12Z | - |
dc.date.available | 2016-07-06T04:28:12Z | - |
dc.date.created | 2016-06-07 | - |
dc.date.created | 2016-06-07 | - |
dc.date.issued | 2010-08 | - |
dc.identifier.citation | LANGMUIR, v.26, no.16, pp.13038 - 13043 | - |
dc.identifier.issn | 0743-7463 | - |
dc.identifier.uri | http://hdl.handle.net/10203/209579 | - |
dc.description.abstract | We introduce a new approach for stabilizing oil-in-water nanoemulsions using a semisolid interphase formed by the phase separation of amphiphilic block copolymers from the organic phase. This system is illustrated using an amphiphilic diblock copolymer, poly(ethylene oxide)-block-poly(epsilon-caprolactone) (PEO-b-PCL), with commonly used oils. PEO-b-PCL can be miscible with oil at elevated temperatures (70-80 degrees C); however, polymer/oil demixing occurs as the temperature drops below the melting temperature of PEO-b-PCL (similar to 55 degrees C). A homogeneous polymer/oil mixture was dispersed in water at 80 degrees C to generate embryonic emulsions, and then the emulsion size was reduced to a nanometer range through microfluidic homogenization. The structure of the generated nanoemulsions is irreversibly frozen as they are cooled down to ambient temperature. The nanoemulsions stabilized by PEO-b-PCL show the excellent colloidal stability against thermal and chemical stresses, exhibiting no significant changes in the size distribution during incubation for 4 months at ambient temperature or 10 days at 60 degrees C. This study demonstrates that PEO-b-PCL is an attractive emulsifying material for practical nanoemulsion formulations requiring structural stability under a broad range of conditions. | - |
dc.language | English | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.subject | NANO-EMULSIONS | - |
dc.subject | COPOLYMER MICELLES | - |
dc.subject | NANOEMULSION | - |
dc.subject | OIL | - |
dc.subject | SURFACTANTS | - |
dc.subject | DELIVERY | - |
dc.subject | EMULSIFICATION | - |
dc.subject | NANOPARTICLES | - |
dc.subject | OPTIMIZATION | - |
dc.subject | FORMULATIONS | - |
dc.title | Nanosized Emulsions Stabilized by Semisolid Polymer interphase | - |
dc.type | Article | - |
dc.identifier.wosid | 000280667900004 | - |
dc.identifier.scopusid | 2-s2.0-77955521836 | - |
dc.type.rims | ART | - |
dc.citation.volume | 26 | - |
dc.citation.issue | 16 | - |
dc.citation.beginningpage | 13038 | - |
dc.citation.endingpage | 13043 | - |
dc.citation.publicationname | LANGMUIR | - |
dc.identifier.doi | 10.1021/la102084f | - |
dc.contributor.localauthor | Nam, Yoon Sung | - |
dc.contributor.nonIdAuthor | Kim, Jin-Woong | - |
dc.contributor.nonIdAuthor | Shim, Jongwon | - |
dc.contributor.nonIdAuthor | Han, Sang Hoon | - |
dc.contributor.nonIdAuthor | Kim, Han Kon | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | NANO-EMULSIONS | - |
dc.subject.keywordPlus | COPOLYMER MICELLES | - |
dc.subject.keywordPlus | NANOEMULSION | - |
dc.subject.keywordPlus | OIL | - |
dc.subject.keywordPlus | SURFACTANTS | - |
dc.subject.keywordPlus | DELIVERY | - |
dc.subject.keywordPlus | EMULSIFICATION | - |
dc.subject.keywordPlus | NANOPARTICLES | - |
dc.subject.keywordPlus | OPTIMIZATION | - |
dc.subject.keywordPlus | FORMULATIONS | - |
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