Isoplatensimycin: Synthesis and biological evaluation

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Isoplatensimycin, a novel analog of platensimycin, was synthesized via intramolecular dipolar cycloaddition of a carbonyl ylide. Isoplatensimycin showed little activities against strains of Staphylococcus aureus, but exhibited activities against some vancomycin-resistant enteroccoci. (C) 2009 Elsevier Ltd. All rights reserved.
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Issue Date
2009-08
Language
English
Article Type
Article
Keywords

FORMAL SYNTHESIS; ENANTIOSELECTIVE ROUTE; PLATENSIMYCIN ANALOGS; OXATETRACYCLIC CORE; (+/-)-PLATENSIMYCIN; STRATEGY

Citation

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.19, no.16, pp.4601 - 4602

ISSN
0960-894X
DOI
10.1016/j.bmcl.2009.06.092
URI
http://hdl.handle.net/10203/209146
Appears in Collection
BS-Journal Papers(저널논문)
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