Human body communication (HBC) is a new technology for mobile and wearable devices operating over body area networks. In HBC, the body is used as a medium for transmitting data between devices to replace wired and wireless technologies. This study examines the bit error rate (BER) degradation experienced by HBC systems under the presence of co-channel interference. A degradation model is proposed to estimate the change in BER, and a selective simulation method is proposed to obtain the BER performance with a small exceedance probability and a small number of BER samples