DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김권일 | ko |
dc.contributor.author | 방효은 | ko |
dc.contributor.author | 이기백 | ko |
dc.contributor.author | 최정균 | ko |
dc.date.accessioned | 2016-07-04T02:04:48Z | - |
dc.date.available | 2016-07-04T02:04:48Z | - |
dc.date.created | 2016-04-27 | - |
dc.date.created | 2016-04-27 | - |
dc.date.issued | 2015-06 | - |
dc.identifier.citation | Genomics & Informatics, v.13, no.2, pp.40 - 44 | - |
dc.identifier.issn | 1598-866X | - |
dc.identifier.uri | http://hdl.handle.net/10203/208876 | - |
dc.description.abstract | DNA microarray and next-generation sequencing provide data that can be used for the genetic analysis of multiple quantitative traits such as gene expression levels, transcription factor binding profiles, and epigenetic signatures. In particular, chromatin opening is tightly coupled with gene transcription. To understand how these two processes are genetically regulated and associated with each other, we examined the changes of chromatin accessibility and gene expression in response to genetic variation by means of quantitative trait loci mapping. Regulatory patterns commonly observed in yeast and human across different technical platforms and experimental designs suggest a higher genetic complexity of transcription regulation in contrast to a more robust genetic architecture of chromatin regulation. | - |
dc.language | Korean | - |
dc.publisher | 한국유전체학회 | - |
dc.title | Genetic Architecture of Transcription and Chromatin Regulation | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.citation.volume | 13 | - |
dc.citation.issue | 2 | - |
dc.citation.beginningpage | 40 | - |
dc.citation.endingpage | 44 | - |
dc.citation.publicationname | Genomics & Informatics | - |
dc.identifier.kciid | ART002009819 | - |
dc.contributor.localauthor | 최정균 | - |
dc.subject.keywordAuthor | epigenetic process | - |
dc.subject.keywordAuthor | gene expression | - |
dc.subject.keywordAuthor | quantitative trait loci | - |
dc.subject.keywordAuthor | regulatory regions | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.