DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, SangYup | ko |
dc.contributor.author | Lee, Y | ko |
dc.contributor.author | Wang, FL | ko |
dc.date.accessioned | 2010-12-01T09:05:36Z | - |
dc.date.available | 2010-12-01T09:05:36Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 1999-11 | - |
dc.identifier.citation | BIOTECHNOLOGY AND BIOENGINEERING, v.65, no.3, pp.363 - 368 | - |
dc.identifier.issn | 0006-3592 | - |
dc.identifier.uri | http://hdl.handle.net/10203/20608 | - |
dc.description.abstract | A novel and efficient method for the production of enantiomerically pure (R)-(-)-hydroxycarboxylic acids by in vivo depolymerization of microbial polyester polyhydroxyalkanoates (PHAs) was developed. Using this method, several model compounds, (R)-(-)-3-hydroxyalkanoic acids, consisting of 4 to 12 carbon atoms, and (R)-(-)-3-hydroxy-5-phenylvaleric acid, could be prepared, in particular, (R)-(-)-3-hydroxybutyric acid could be efficiently prepared by this method. By providing the environmental condition in which cells possess high activity of intracellular PHA depolymerase and low activity of (R)-(-)-3-hydroxybutyric acid dehydrogenase, (R)-(-)-3-hydroxybutyric acid could be produced with a yield of 96% in only 30 min by in vivo depolymerization of polyhydroxybutyrate (PHB) accumulated in Alcaligenes latus. (C) 1999 John Wiley & Sons, Inc. | - |
dc.language | English | - |
dc.language.iso | en_US | en |
dc.publisher | JOHN WILEY SONS INC | - |
dc.title | Chiral compounds from bacterial polyesters: Sugars to plastics to fine chemicals | - |
dc.type | Article | - |
dc.identifier.wosid | 000082788300015 | - |
dc.identifier.scopusid | 2-s2.0-0344761959 | - |
dc.type.rims | ART | - |
dc.citation.volume | 65 | - |
dc.citation.issue | 3 | - |
dc.citation.beginningpage | 363 | - |
dc.citation.endingpage | 368 | - |
dc.citation.publicationname | BIOTECHNOLOGY AND BIOENGINEERING | - |
dc.embargo.liftdate | 9999-12-31 | - |
dc.embargo.terms | 9999-12-31 | - |
dc.contributor.localauthor | Lee, SangYup | - |
dc.contributor.nonIdAuthor | Lee, Y | - |
dc.contributor.nonIdAuthor | Wang, FL | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | chirality | - |
dc.subject.keywordAuthor | chiral compound | - |
dc.subject.keywordAuthor | polyester | - |
dc.subject.keywordAuthor | (R)-(-)-hydroxycarboxylic acid | - |
dc.subject.keywordAuthor | polyhydroxyalkanoate (PHA) | - |
dc.subject.keywordAuthor | in vivo depolymerization | - |
dc.subject.keywordPlus | FED-BATCH CULTURE | - |
dc.subject.keywordPlus | PSEUDOMONAS-OLEOVORANS | - |
dc.subject.keywordPlus | POLY(BETA-HYDROXYALKANOATES) | - |
dc.subject.keywordPlus | POLYHYDROXYALKANOATES | - |
dc.subject.keywordPlus | ACIDS | - |
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