DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Changhan | ko |
dc.contributor.author | Wigren, Edvard | ko |
dc.contributor.author | Trcek, Janja | ko |
dc.contributor.author | Peters, Verena | ko |
dc.contributor.author | Kim, Jihong | ko |
dc.contributor.author | Hasni, Muhammad Sharif | ko |
dc.contributor.author | Nimtz, Manfred | ko |
dc.contributor.author | Lindqvist, Ylva | ko |
dc.contributor.author | Park, Chankyu | ko |
dc.contributor.author | Curth, Ute | ko |
dc.contributor.author | Luensdorf, Heinrich | ko |
dc.contributor.author | Romling, Ute | ko |
dc.date.accessioned | 2016-04-20T06:51:48Z | - |
dc.date.available | 2016-04-20T06:51:48Z | - |
dc.date.created | 2016-01-04 | - |
dc.date.created | 2016-01-04 | - |
dc.date.issued | 2015-11 | - |
dc.identifier.citation | ENVIRONMENTAL MICROBIOLOGY, v.17, no.11, pp.4511 - 4526 | - |
dc.identifier.issn | 1462-2912 | - |
dc.identifier.uri | http://hdl.handle.net/10203/205535 | - |
dc.description.abstract | Pseudomonas aeruginosa is a highly successful nosocomial pathogen capable of causing a wide variety of infectionswithclone C strains most prevalentworldwide. In this study, we initially characterize a molecular mechanism of survival unique to clone C strains. We identified aP.aeruginosa clone C-specific genomic island (PACGI-1) that contains the highly expressed small heat shock protein sHsp20c, the founding member of a novel subclass of class B bacterial small heat shock proteins. sHsp20c and adjacent gene products are involved in resistance against heat shock.Heat stable sHsp20c is unconventionally expressed in stationary phase in a wide temperature range from 20 to 42 degrees C. PurifiedsHsp20c has characteristic features of small heat shock protein class B as it is monodisperse, forms sphere-like 24-meric oligomers and exhibits significant chaperone activity. As theP.aeruginosaclone C population is significantly more heat shock resistant than genetically unrelated P.aeruginosa strains without sHsp20c, the horizontally acquired shsp20c operon might contribute to the survival of worldwide-distributed clone C strains. | - |
dc.language | English | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.subject | ESCHERICHIA-COLI | - |
dc.subject | CYSTIC-FIBROSIS | - |
dc.subject | MOLECULAR CHAPERONE | - |
dc.subject | SEDIMENTATION EQUILIBRIUM | - |
dc.subject | GENOMIC ISLANDS | - |
dc.subject | EVOLUTION | - |
dc.subject | EXPRESSION | - |
dc.subject | ENVIRONMENT | - |
dc.subject | INFECTIONS | - |
dc.subject | GENES | - |
dc.title | A novel protein quality control mechanism contributes to heat shock resistance of worldwide-distributed Pseudomonas aeruginosa clone C strains | - |
dc.type | Article | - |
dc.identifier.wosid | 000366139500028 | - |
dc.identifier.scopusid | 2-s2.0-84949318301 | - |
dc.type.rims | ART | - |
dc.citation.volume | 17 | - |
dc.citation.issue | 11 | - |
dc.citation.beginningpage | 4511 | - |
dc.citation.endingpage | 4526 | - |
dc.citation.publicationname | ENVIRONMENTAL MICROBIOLOGY | - |
dc.identifier.doi | 10.1111/1462-2920.12915 | - |
dc.contributor.localauthor | Park, Chankyu | - |
dc.contributor.nonIdAuthor | Lee, Changhan | - |
dc.contributor.nonIdAuthor | Wigren, Edvard | - |
dc.contributor.nonIdAuthor | Trcek, Janja | - |
dc.contributor.nonIdAuthor | Peters, Verena | - |
dc.contributor.nonIdAuthor | Hasni, Muhammad Sharif | - |
dc.contributor.nonIdAuthor | Nimtz, Manfred | - |
dc.contributor.nonIdAuthor | Lindqvist, Ylva | - |
dc.contributor.nonIdAuthor | Curth, Ute | - |
dc.contributor.nonIdAuthor | Luensdorf, Heinrich | - |
dc.contributor.nonIdAuthor | Romling, Ute | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | CYSTIC-FIBROSIS | - |
dc.subject.keywordPlus | MOLECULAR CHAPERONE | - |
dc.subject.keywordPlus | SEDIMENTATION EQUILIBRIUM | - |
dc.subject.keywordPlus | GENOMIC ISLANDS | - |
dc.subject.keywordPlus | EVOLUTION | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | ENVIRONMENT | - |
dc.subject.keywordPlus | INFECTIONS | - |
dc.subject.keywordPlus | GENES | - |
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