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College of Engineering(공과대학)Dept. of Nuclear and Quantum Engineering(원자력및양자공학과)NE-Journal Papers(저널논문)

In silico analysis of lactate producing metabolic network in Lactococcus lactis

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dc.contributor.authorNam, JWko
dc.contributor.authorHan, KHko
dc.contributor.authorYoon, ESko
dc.contributor.authorShin, Dko
dc.contributor.authorJin, JHko
dc.contributor.authorLee, DHko
dc.contributor.authorLee, SangYupko
dc.contributor.authorLee, Jko
dc.date.accessioned2010-11-17T08:42:20Z-
dc.date.available2010-11-17T08:42:20Z-
dc.date.created2012-02-06-
dc.date.created2012-02-06-
dc.date.created2012-02-06-
dc.date.issued2004-12-
dc.identifier.citationENZYME AND MICROBIAL TECHNOLOGY, v.35, pp.654 - 662-
dc.identifier.issn0141-0229-
dc.identifier.urihttp://hdl.handle.net/10203/20105-
dc.description.abstractToday the importance of in silico experiment grows bigger than before by the advance of computing power. More detailed mathematical modeling handled by simulation can produce more reasonable and meaningful results. In this research, we suggest the metabolic network of Lactococcus lactis for aerobic condition. Using a mathematical model, we observed the effect of enzymes on lactate production using flux distribution analysis, metabolic control analysis, and in silico experiment by biochemical simulation software. Each analysis showed some different results because of their characteristics but some key enzymes for lactate production were found from them. (C) 2004 Elsevier Inc. All rights reserved.-
dc.description.sponsorshipThis work was supported by the Korean Systems Biology Research Grant (M10309020000-03B5002-00000) from the Ministry of Science and Technology.en
dc.languageEnglish-
dc.language.isoen_USen
dc.publisherELSEVIER SCIENCE INC-
dc.titleIn silico analysis of lactate producing metabolic network in Lactococcus lactis-
dc.typeArticle-
dc.identifier.wosid000225263000029-
dc.identifier.scopusid2-s2.0-7544230183-
dc.type.rimsART-
dc.citation.volume35-
dc.citation.beginningpage654-
dc.citation.endingpage662-
dc.citation.publicationnameENZYME AND MICROBIAL TECHNOLOGY-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.contributor.localauthorLee, SangYup-
dc.contributor.nonIdAuthorNam, JW-
dc.contributor.nonIdAuthorHan, KH-
dc.contributor.nonIdAuthorYoon, ES-
dc.contributor.nonIdAuthorShin, D-
dc.contributor.nonIdAuthorJin, JH-
dc.contributor.nonIdAuthorLee, DH-
dc.contributor.nonIdAuthorLee, J-
dc.type.journalArticleArticle; Proceedings Paper-
dc.subject.keywordAuthorLactococcus lactis-
dc.subject.keywordAuthormetabolic engineering-
dc.subject.keywordAuthormetabolic control analysis-
dc.subject.keywordAuthorpyruvate branch-
dc.subject.keywordPlusSYSTEMS-
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