Antimicrobial biomaterials based on carbon nanotubes dispersed in poly(lactic-co-glycolic acid)

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dc.contributor.authorAslan, Seymako
dc.contributor.authorLoebick, Codruta Zoicanko
dc.contributor.authorKang, Seoktaeko
dc.contributor.authorElimelech, Menachemko
dc.contributor.authorPfefferle, LDko
dc.contributor.authorVan Tassel, Paul R.ko
dc.date.accessioned2015-11-20T07:45:38Z-
dc.date.available2015-11-20T07:45:38Z-
dc.date.created2015-08-26-
dc.date.created2015-08-26-
dc.date.created2015-08-26-
dc.date.issued2010-
dc.identifier.citationNANOSCALE, v.2, no.9, pp.1789 - 1794-
dc.identifier.issn2040-3364-
dc.identifier.urihttp://hdl.handle.net/10203/200863-
dc.description.abstractBiomaterials that inactivate microbes are needed to eliminate medical device infections. We investigate here the antimicrobial nature of single-walled carbon nanotubes (SWNTs) incorporated within the biomedical polymer poly(lactic-co-glycolic acid) (PLGA). We find Escherichia coli and Staphylococcus epidermidis viability and metabolic activity to be significantly diminished in the presence of SWNT-PLGA, and to correlate with SWNT length and concentration (<2% by weight). Up to 98% of bacteria die within one hour on SWNT-PLGA versus 15-20% on pure PLGA. Shorter SWNTs are more toxic, possibly due to increased density of open tube ends. This study demonstrates the potential usefulness of SWNT-PLGA as an antimicrobial biomaterial.-
dc.languageEnglish-
dc.publisherROYAL SOC CHEMISTRY-
dc.titleAntimicrobial biomaterials based on carbon nanotubes dispersed in poly(lactic-co-glycolic acid)-
dc.typeArticle-
dc.identifier.wosid000281613800031-
dc.identifier.scopusid2-s2.0-77956389540-
dc.type.rimsART-
dc.citation.volume2-
dc.citation.issue9-
dc.citation.beginningpage1789-
dc.citation.endingpage1794-
dc.citation.publicationnameNANOSCALE-
dc.identifier.doi10.1039/c0nr00329h-
dc.contributor.localauthorKang, Seoktae-
dc.contributor.nonIdAuthorAslan, Seyma-
dc.contributor.nonIdAuthorLoebick, Codruta Zoican-
dc.contributor.nonIdAuthorElimelech, Menachem-
dc.contributor.nonIdAuthorPfefferle, LD-
dc.contributor.nonIdAuthorVan Tassel, Paul R.-
dc.type.journalArticleArticle-
dc.subject.keywordPlusIN-VITRO ACTIVITY-
dc.subject.keywordPlusSURFACE-
dc.subject.keywordPlusCOATINGS-
dc.subject.keywordPlusCONTACT-
dc.subject.keywordPlusRELEASE-
dc.subject.keywordPlusPOLYURETHANES-
dc.subject.keywordPlusPERFORMANCE-
dc.subject.keywordPlusINFECTION-
dc.subject.keywordPlusPATHOGENS-
dc.subject.keywordPlusCOMPOSITE-
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