DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Jung-Hun | ko |
dc.contributor.author | Park, Ki-Soo | ko |
dc.contributor.author | Lee, Kyungmee | ko |
dc.contributor.author | Jang, Hyowon | ko |
dc.contributor.author | Park, Hyun-Gyu | ko |
dc.date.accessioned | 2015-04-07T05:10:32Z | - |
dc.date.available | 2015-04-07T05:10:32Z | - |
dc.date.created | 2014-11-25 | - |
dc.date.created | 2014-11-25 | - |
dc.date.created | 2014-11-25 | - |
dc.date.issued | 2015-01 | - |
dc.identifier.citation | BIOTECHNOLOGY JOURNAL, v.10, no.1, pp.45 - 55 | - |
dc.identifier.issn | 1860-6768 | - |
dc.identifier.uri | http://hdl.handle.net/10203/195292 | - |
dc.description.abstract | In order to achieve multiplex screening of genetic variations, multiplex amplification of target genomic DNA is necessary. Universal amplification technology meets this requirement by simultaneously amplifying a number of different regions within the target genomic DNA using a single pair of universal primers and thus eliminating the limitations associated with the use of multiple pairs of primers. We comprehensively review universal probe amplification and its use with multiplex technologies for the identification of the most representative genetic variation, i. e. single nucleotide polymorphisms. The progress and key issues relating to universal probe amplification are discussed and the representative technologies are summarized with an emphasis on their application for the identification of susceptibility to human diseases. | - |
dc.language | English | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Universal probe amplification: Multiplex screening technologies for genetic variations | - |
dc.type | Article | - |
dc.identifier.wosid | 000348058200008 | - |
dc.identifier.scopusid | 2-s2.0-84921510689 | - |
dc.type.rims | ART | - |
dc.citation.volume | 10 | - |
dc.citation.issue | 1 | - |
dc.citation.beginningpage | 45 | - |
dc.citation.endingpage | 55 | - |
dc.citation.publicationname | BIOTECHNOLOGY JOURNAL | - |
dc.identifier.doi | 10.1002/biot.201400219 | - |
dc.contributor.localauthor | Park, Hyun-Gyu | - |
dc.contributor.nonIdAuthor | Lee, Kyungmee | - |
dc.contributor.nonIdAuthor | Jang, Hyowon | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Review | - |
dc.subject.keywordAuthor | Analytical biotechnology | - |
dc.subject.keywordAuthor | Genetic variation | - |
dc.subject.keywordAuthor | Microarrays | - |
dc.subject.keywordAuthor | Multiplex screening | - |
dc.subject.keywordAuthor | Universal amplification | - |
dc.subject.keywordPlus | MOLECULAR INVERSION PROBES | - |
dc.subject.keywordPlus | SINGLE-NUCLEOTIDE POLYMORPHISMS | - |
dc.subject.keywordPlus | COPY NUMBER ALTERATIONS | - |
dc.subject.keywordPlus | LIGASE CHAIN-REACTION | - |
dc.subject.keywordPlus | ZIP-CODE MICROARRAY | - |
dc.subject.keywordPlus | CAPILLARY-ELECTROPHORESIS | - |
dc.subject.keywordPlus | GENOMIC REARRANGEMENTS | - |
dc.subject.keywordPlus | SPANISH POPULATION | - |
dc.subject.keywordPlus | BEAD ARRAYS | - |
dc.subject.keywordPlus | MLPA | - |
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