DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hong, Daewha | ko |
dc.contributor.author | Lee, Hojae | ko |
dc.contributor.author | Ko, Eun Hyea | ko |
dc.contributor.author | Lee, Juno | ko |
dc.contributor.author | Cho, Hyeoncheol | ko |
dc.contributor.author | Park, Matthew Y | ko |
dc.contributor.author | Yang, Sung Ho | ko |
dc.contributor.author | Choi, In-Sung | ko |
dc.date.accessioned | 2015-04-07T02:39:57Z | - |
dc.date.available | 2015-04-07T02:39:57Z | - |
dc.date.created | 2015-01-13 | - |
dc.date.created | 2015-01-13 | - |
dc.date.issued | 2015-01 | - |
dc.identifier.citation | CHEMICAL SCIENCE, v.6, no.1, pp.203 - 208 | - |
dc.identifier.issn | 2041-6520 | - |
dc.identifier.uri | http://hdl.handle.net/10203/195111 | - |
dc.description.abstract | The cytoprotection of individual living cells under in vitro and daily-life conditions is a prerequisite for various cell-based applications including cell therapy, cell-based sensors, regenerative medicine, and even the food industry. In this work, we use a cytocompatible two-step process to encapsulate Saccharomyces cerevisiae in a highly uniform nanometric (<100 nm) shell composed of organic poly(norepinephrine) and inorganic silica layers. The resulting cell-in-shell structure acquires multiple resistance against lytic enzyme, desiccation, and UV-C irradiation. In addition to the UV-C filtering effect of the double-layered shell, the biochemical responses of the encapsulated yeast are suggested to contribute to the observed UV-C tolerance. This work offers a chemical tool for cytoprotecting individual living cells under multiple stresses and also for studying biochemical behavior at the cellular level. | - |
dc.language | English | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.subject | YEAST-CELLS | - |
dc.subject | SILICA | - |
dc.subject | BIOMINERALIZATION | - |
dc.subject | FUNCTIONALIZATION | - |
dc.subject | ENCAPSULATION | - |
dc.subject | PROTEINS | - |
dc.subject | VACCINES | - |
dc.title | Organic/inorganic double-layered shells for multiple cytoprotection of individual living cells | - |
dc.type | Article | - |
dc.identifier.wosid | 000345901600019 | - |
dc.identifier.scopusid | 2-s2.0-84915819878 | - |
dc.type.rims | ART | - |
dc.citation.volume | 6 | - |
dc.citation.issue | 1 | - |
dc.citation.beginningpage | 203 | - |
dc.citation.endingpage | 208 | - |
dc.citation.publicationname | CHEMICAL SCIENCE | - |
dc.identifier.doi | 10.1039/c4sc02789b | - |
dc.contributor.localauthor | Choi, In-Sung | - |
dc.contributor.nonIdAuthor | Cho, Hyeoncheol | - |
dc.contributor.nonIdAuthor | Yang, Sung Ho | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | YEAST-CELLS | - |
dc.subject.keywordPlus | SILICA | - |
dc.subject.keywordPlus | BIOMINERALIZATION | - |
dc.subject.keywordPlus | FUNCTIONALIZATION | - |
dc.subject.keywordPlus | ENCAPSULATION | - |
dc.subject.keywordPlus | PROTEINS | - |
dc.subject.keywordPlus | VACCINES | - |
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