A rationally designed macrocyclic cavitand that kills bacteria with high efficacy and good selectivity

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An amphiphilic macrocyclic cavitand that shows good antibacterial activity, comparable to that of peptide-based antibiotics was developed by rational design and its antibacterial selectivity over mammalian cells was examined.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2007
Language
English
Article Type
Article
Keywords

ANTIMICROBIAL PEPTIDES; CELL SELECTIVITY; DERIVATIVES; MEMBRANES; RESIDUES; AGENTS

Citation

CHEMICAL COMMUNICATIONS, no.11, pp.1151 - 1153

ISSN
1359-7345
DOI
10.1039/b617005f
URI
http://hdl.handle.net/10203/192429
Appears in Collection
BS-Journal Papers(저널논문)
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