DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Junsoo | ko |
dc.contributor.author | Lee, Myung-Shin | ko |
dc.contributor.author | Yoo, Seung-Min | ko |
dc.contributor.author | Jeong, Kwi Wan | ko |
dc.contributor.author | Lee, Daeyoup | ko |
dc.contributor.author | Choe, Joonho | ko |
dc.contributor.author | Seo, Taegun | ko |
dc.date.accessioned | 2010-09-01T06:24:15Z | - |
dc.date.available | 2010-09-01T06:24:15Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2007-11 | - |
dc.identifier.citation | JOURNAL OF VIROLOGY, v.81, no.22, pp.12680 - 12684 | - |
dc.identifier.issn | 0022-538X | - |
dc.identifier.uri | http://hdl.handle.net/10203/19081 | - |
dc.description.abstract | Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi's sarcoma. The open reading frame (K9) of KSHV encodes viral interferon regulatory factor 1 (vIRF1), which functions as a repressor of interferon-mediated signal transduction. The amino-terminal region of vIRF1 displays significant homology to the DNA-binding domain of cellular interferon regulatory factors, supporting the theory that the protein interacts with specific DNA sequences. Here, we identify the consensus sequence of vIRF1-bindinh sites from a pool of random oligonucleotides. Moreover, our data show that vIRF1 interacts with the K3:viral dihydrofolate reductase:viral interleukin 6 promoter region in the KSHV genome. | - |
dc.language | English | - |
dc.language.iso | en_US | en |
dc.publisher | AMER SOC MICROBIOLOGY | - |
dc.subject | CELL-DEATH | - |
dc.subject | TRANSCRIPTION | - |
dc.subject | INHIBITION | - |
dc.subject | REPRESSES | - |
dc.subject | PATHWAY | - |
dc.subject | PROTEIN | - |
dc.subject | BINDS | - |
dc.subject | P300 | - |
dc.subject | BETA | - |
dc.subject | P53 | - |
dc.title | Identification of the DNA sequence interacting with Kaposis sarcoma-associated herpesvirus viral interferon regulatory factor 1 | - |
dc.type | Article | - |
dc.identifier.wosid | 000254065400059 | - |
dc.identifier.scopusid | 2-s2.0-36049016187 | - |
dc.type.rims | ART | - |
dc.citation.volume | 81 | - |
dc.citation.issue | 22 | - |
dc.citation.beginningpage | 12680 | - |
dc.citation.endingpage | 12684 | - |
dc.citation.publicationname | JOURNAL OF VIROLOGY | - |
dc.identifier.doi | 10.1128/JVI.00556-07 | - |
dc.contributor.localauthor | Lee, Daeyoup | - |
dc.contributor.localauthor | Choe, Joonho | - |
dc.contributor.nonIdAuthor | Park, Junsoo | - |
dc.contributor.nonIdAuthor | Lee, Myung-Shin | - |
dc.contributor.nonIdAuthor | Yoo, Seung-Min | - |
dc.contributor.nonIdAuthor | Jeong, Kwi Wan | - |
dc.contributor.nonIdAuthor | Seo, Taegun | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | CELL-DEATH | - |
dc.subject.keywordPlus | TRANSCRIPTION | - |
dc.subject.keywordPlus | INHIBITION | - |
dc.subject.keywordPlus | REPRESSES | - |
dc.subject.keywordPlus | PATHWAY | - |
dc.subject.keywordPlus | PROTEIN | - |
dc.subject.keywordPlus | BINDS | - |
dc.subject.keywordPlus | P300 | - |
dc.subject.keywordPlus | BETA | - |
dc.subject.keywordPlus | P53 | - |
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