Enhancement of the photocytotoxic efficiency of sub-12 nm therapeutic polymeric micelles with increased co-localisation in mitochondria
We engineered phototherapeutic sub-12 nm-sized polymeric micelles to treat malignant brain tumours (MBTs). The engineered nanoparticles in MBT cells enhanced the photocytotoxic efficiency more than 2.5-fold compared with parental and PEGylated photosensitisers (PSs). Increased subcellular co-localisation of PSs in mitochondria was observed.
- Publisher
- ROYAL SOC CHEMISTRY
- Issue Date
- 2013-12
- Language
- English
- Article Type
- Article
- Citation
CHEMICAL COMMUNICATIONS, v.49, no.98, pp.11476 - 11478
- ISSN
- 1359-7345
- Appears in Collection
- MSE-Journal Papers(저널논문)BS-Journal Papers(저널논문)BiS-Journal Papers(저널논문)
- Files in This Item
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