STAMPing into Mitochondria
Six transmembrane protein of prostate 2 (STAMP2) is a protein that has been extensively studied due to its association with prostate cancer. Currently, STAMP2 is well known for its critical role in metabolism and modulating inflammatory signals. Even so, the molecular mechanism of STAMP2 activity and its downstream effectors are still largely unknown. Here, we review the current knowledge of STAMP2, and suggest possible explanations for some of its less well-understood features. A few studies suggest that STAMP2 may interact with mitochondria. Considering STAMP2 functions as a potential component of mitochondrial biology may yield valuable insight into this protein.
- Publisher
- IVYSPRING INT PUBL
- Issue Date
- 2014
- Language
- English
- Article Type
- Review
- Keywords
ADIPOSE-RELATED PROTEIN; NECROSIS-FACTOR-ALPHA; 6 TRANSMEMBRANE PROTEIN; VIRUS HBX PROTEIN; PROSTATE-CANCER; INSULIN-RESISTANCE; MOLECULAR-CLONING; HUMAN ADIPOCYTES; STEAP PROTEINS; INFLAMMATION
- Citation
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, v.10, no.3, pp.321 - 326
- ISSN
- 1449-2288
- Appears in Collection
- RIMS Journal Papers
- Files in This Item
- 000332272700009.pdf(636.07 kB)Download
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