Selective and Sensitive Superoxide Detection with a New Diselenide-Based Molecular Probe in Living Breast Cancer Cells
A diselenide-based BODIPY probe was prepared; it was found to be sensitive and selective for superoxide in giving [-Se(O)Se(O)-] oxidation. Probing was reversible through the use of biothiols; Se-77 NMR and other types of spectroscopy were employed. Practical medicinal utility was demonstrated in MCF-7/ADR cancer cells.
- Publisher
- AMER CHEMICAL SOC
- Issue Date
- 2014-01
- Language
- English
- Article Type
- Article
- Keywords
PHORBOL-MYRISTATE ACETATE; FLUORESCENT-PROBE; OXIDATIVE STRESS; ANTIOXIDANT ACTIVITY; DIARYL DISELENIDES; TURN-ON; CHEMISTRY; BODIPY; OXYGEN; SELENIDE
- Citation
ORGANIC LETTERS, v.16, no.2, pp.410 - 412
- ISSN
- 1523-7060
- Appears in Collection
- BS-Journal Papers(저널논문)CH-Journal Papers(저널논문)
- Files in This Item
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