Selective detection of cysteine over homocysteine and glutathione by a bis(bromoacetyl)fluorescein probe

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dc.contributor.authorHong, Keum-Heeko
dc.contributor.authorLim, Soo-Yeonko
dc.contributor.authorYun, Mi-Yeonko
dc.contributor.authorLim, Joo-Wonko
dc.contributor.authorWoo, Je-Hyukko
dc.contributor.authorKwon, Hyockmanko
dc.contributor.authorKim, Hae-Joko
dc.date.accessioned2013-08-08T05:59:47Z-
dc.date.available2013-08-08T05:59:47Z-
dc.date.created2013-06-24-
dc.date.created2013-06-24-
dc.date.issued2013-06-
dc.identifier.citationTETRAHEDRON LETTERS, v.54, no.23, pp.3003 - 3006-
dc.identifier.issn0040-4039-
dc.identifier.urihttp://hdl.handle.net/10203/174716-
dc.description.abstractA bromoacetyl functionalized fluorescein chemodosimeter (1) was utilized as a fluorescent probe for cysteine. The probe showed a selective and sensitive response to cysteine over homocysteine and glutathione in aqueous buffer through a rapid cyclization reaction. When cysteine was added, a fast fluorescence turn-on change of 1 was observed, thus allowing cysteine to be discriminated from other biothiols and micromolar concentrations of cysteine to be detected by the naked eye. (C) 2013 Elsevier Ltd. All rights reserved.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.subjectTURN-ON PROBE-
dc.subjectFLUORESCENCE-
dc.subjectDISEASE-
dc.subjectSENSOR-
dc.titleSelective detection of cysteine over homocysteine and glutathione by a bis(bromoacetyl)fluorescein probe-
dc.typeArticle-
dc.identifier.wosid000318832200026-
dc.identifier.scopusid2-s2.0-84877728193-
dc.type.rimsART-
dc.citation.volume54-
dc.citation.issue23-
dc.citation.beginningpage3003-
dc.citation.endingpage3006-
dc.citation.publicationnameTETRAHEDRON LETTERS-
dc.identifier.doi10.1016/j.tetlet.2013.03.119-
dc.contributor.localauthorLim, Joo-Won-
dc.contributor.nonIdAuthorHong, Keum-Hee-
dc.contributor.nonIdAuthorLim, Soo-Yeon-
dc.contributor.nonIdAuthorYun, Mi-Yeon-
dc.contributor.nonIdAuthorWoo, Je-Hyuk-
dc.contributor.nonIdAuthorKwon, Hyockman-
dc.contributor.nonIdAuthorKim, Hae-Jo-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorChemodosimeter-
dc.subject.keywordAuthorCysteine-
dc.subject.keywordAuthorFluorescence-
dc.subject.keywordAuthorProbe-
dc.subject.keywordPlusTURN-ON PROBE-
dc.subject.keywordPlusFLUORESCENCE-
dc.subject.keywordPlusDISEASE-
dc.subject.keywordPlusSENSOR-
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