DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Chang-Hoon | ko |
dc.contributor.author | Ahn, Jae-Hyuk | ko |
dc.contributor.author | Kim, Jee-Yeon | ko |
dc.contributor.author | Choi, Ji-Min | ko |
dc.contributor.author | Lim, Kyung-Choon | ko |
dc.contributor.author | Park, Tae-Jung | ko |
dc.contributor.author | Heo, Nam-Su | ko |
dc.contributor.author | Lee, Hee-Gu | ko |
dc.contributor.author | Kim, Jong-Wan | ko |
dc.contributor.author | Choi, Yang-Kyu | ko |
dc.date.accessioned | 2013-08-08T05:43:34Z | - |
dc.date.available | 2013-08-08T05:43:34Z | - |
dc.date.created | 2013-03-08 | - |
dc.date.created | 2013-03-08 | - |
dc.date.issued | 2013-03 | - |
dc.identifier.citation | BIOSENSORS & BIOELECTRONICS, v.41, pp.322 - 327 | - |
dc.identifier.issn | 0956-5663 | - |
dc.identifier.uri | http://hdl.handle.net/10203/174531 | - |
dc.description.abstract | Most of point-of-care testing (POCT) to improve facilitates in diagnosis, treatment, and monitoring of patients. POCT technique has still remained a quantitatively and accurately detective effect. In this article, we demonstrated that real human C-reactive protein (CRP) in serum was detected for a chip-based point-of-care testing application based on a nanogap-embedded field effect transistor (FET), and the results were compared with those obtained via the enzyme-linked immunosorbent assay (ELISA) method. The limit of detection (LOD), determined from the standard curve, was 0.1 ng/ml, which is comparable to that of commercialized ELISAs. We evaluated that an improved detection range (0.1 ng/ml to 100 ng/ml) was achieved by comparing with commercialized ELISA. Control experiments to determine selectivity and to discern false-positive/false-negative rates were also performed. This report is the first description of the detection of CRP in human serum using a silicon-based biosensor. (C) 2012 Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.publisher | ELSEVIER ADVANCED TECHNOLOGY | - |
dc.subject | C-REACTIVE PROTEIN | - |
dc.subject | SURFACE-PLASMON RESONANCE | - |
dc.subject | FIELD-EFFECT TRANSISTOR | - |
dc.subject | BIOSENSORS | - |
dc.subject | ELISA | - |
dc.title | CRP detection from serum for chip-based point-of-care testing system | - |
dc.type | Article | - |
dc.identifier.wosid | 000314191300046 | - |
dc.identifier.scopusid | 2-s2.0-84870820491 | - |
dc.type.rims | ART | - |
dc.citation.volume | 41 | - |
dc.citation.beginningpage | 322 | - |
dc.citation.endingpage | 327 | - |
dc.citation.publicationname | BIOSENSORS & BIOELECTRONICS | - |
dc.identifier.doi | 10.1016/j.bios.2012.08.047 | - |
dc.contributor.localauthor | Choi, Yang-Kyu | - |
dc.contributor.nonIdAuthor | Kim, Jee-Yeon | - |
dc.contributor.nonIdAuthor | Choi, Ji-Min | - |
dc.contributor.nonIdAuthor | Lim, Kyung-Choon | - |
dc.contributor.nonIdAuthor | Park, Tae-Jung | - |
dc.contributor.nonIdAuthor | Heo, Nam-Su | - |
dc.contributor.nonIdAuthor | Lee, Hee-Gu | - |
dc.contributor.nonIdAuthor | Kim, Jong-Wan | - |
dc.description.isOpenAccess | N | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | C-reactive protein | - |
dc.subject.keywordAuthor | CRP | - |
dc.subject.keywordAuthor | Nanogap-embedded FET | - |
dc.subject.keywordAuthor | FET-based biosensor | - |
dc.subject.keywordAuthor | Point-of-care testing (POCT) | - |
dc.subject.keywordPlus | C-REACTIVE PROTEIN | - |
dc.subject.keywordPlus | SURFACE-PLASMON RESONANCE | - |
dc.subject.keywordPlus | FIELD-EFFECT TRANSISTOR | - |
dc.subject.keywordPlus | BIOSENSORS | - |
dc.subject.keywordPlus | ELISA | - |
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