A direct surface modification of iron oxide nanoparticles with various poly(amino acid)s for use as magnetic resonance probes

Cited 31 time in webofscience Cited 0 time in scopus
  • Hit : 692
  • Download : 1515
DC FieldValueLanguage
dc.contributor.authorYang, Hee-Manko
dc.contributor.authorPark, Chan-Wooko
dc.contributor.authorAhn, Tae-Binko
dc.contributor.authorJung, Bo-Kyungko
dc.contributor.authorSeo, Bum-Kyoungko
dc.contributor.authorPark, Jung-Hwanko
dc.contributor.authorKim, Jong-Dukko
dc.date.accessioned2013-03-12T20:56:45Z-
dc.date.available2013-03-12T20:56:45Z-
dc.date.created2013-01-07-
dc.date.created2013-01-07-
dc.date.issued2013-02-
dc.identifier.citationJOURNAL OF COLLOID AND INTERFACE SCIENCE, v.391, pp.158 - 167-
dc.identifier.issn0021-9797-
dc.identifier.urihttp://hdl.handle.net/10203/103492-
dc.description.abstractWater soluble and biocompatible iron oxide nanoparticles coated with poly(aspartic acid) (PAsp), poly(asparagines) (PAsn), poly(2-hydroxy-ethyl L-aspartamide) (PHEA), and poly-alpha,beta-(N-2-dimethylaminoethyl L-aspartamide) (PDMAEA) were prepared by hydrophobic interaction between hydrophobic iron oxide nanoparticles and each amphiphilic poly(amino acid)s graft polymer. The octadecyl side chain grafted poly(succinimide)(PSI-g-C-18), used as a precursor polymer, was easily aminolyzed with nucleophilic compounds to form various poly(amino acid)s graft polymer (PAsp-g-C-18, PAsn-g-C-18, PHEA-g-C-18, PDMAEA-g-C-18,) and simultaneously stabilize the dispersion of iron oxide nanoparticles in aqueous solution. The diameters of the poly(amino acid)s coated iron oxide nanoparticles (PAIONs) were smaller than 30 nm in aqueous solution, extremely stable in aqueous solutions with a wide range of pH and salt concentrations. Further, all the PAIONs showed excellent MR signal intensities (high r(2) values) and the cellular uptake property of the PAIONs was also evaluated. Crown Copyright (C) 2012 Published by Elsevier Inc. All rights reserved.-
dc.languageEnglish-
dc.publisherACADEMIC PRESS INC ELSEVIER SCIENCE-
dc.subjectPOLY(ETHYLENE GLYCOL)-
dc.subjectCONTRAST AGENT-
dc.subjectDELIVERY-
dc.subjectCANCER-
dc.subjectMETHOTREXATE-
dc.subjectLIPOSOMES-
dc.subjectPOLYMER-
dc.subjectDESIGN-
dc.subjectMEDIA-
dc.subjectCELLS-
dc.titleA direct surface modification of iron oxide nanoparticles with various poly(amino acid)s for use as magnetic resonance probes-
dc.typeArticle-
dc.identifier.wosid000312039000021-
dc.identifier.scopusid2-s2.0-84868663089-
dc.type.rimsART-
dc.citation.volume391-
dc.citation.beginningpage158-
dc.citation.endingpage167-
dc.citation.publicationnameJOURNAL OF COLLOID AND INTERFACE SCIENCE-
dc.identifier.doi10.1016/j.jcis.2012.09.044-
dc.contributor.localauthorKim, Jong-Duk-
dc.contributor.nonIdAuthorJung, Bo-Kyung-
dc.contributor.nonIdAuthorSeo, Bum-Kyoung-
dc.contributor.nonIdAuthorPark, Jung-Hwan-
dc.type.journalArticleArticle-
dc.subject.keywordPlusPOLY(ETHYLENE GLYCOL)-
dc.subject.keywordPlusCONTRAST AGENT-
dc.subject.keywordPlusDELIVERY-
dc.subject.keywordPlusCANCER-
dc.subject.keywordPlusMETHOTREXATE-
dc.subject.keywordPlusLIPOSOMES-
dc.subject.keywordPlusPOLYMER-
dc.subject.keywordPlusDESIGN-
dc.subject.keywordPlusMEDIA-
dc.subject.keywordPlusCELLS-
Appears in Collection
CBE-Journal Papers(저널논문)
Files in This Item
78828.pdf(1.46 MB)Download
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 31 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0