Aminoglycoside antibiotics bind to the influenza A virus RNA promoter
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kim, Henna | ko |
| dc.contributor.author | Lee, Mi-Kyung | ko |
| dc.contributor.author | Ko, Junsang | ko |
| dc.contributor.author | Park, Chin-Ju | ko |
| dc.contributor.author | Kim, Meehyein | ko |
| dc.contributor.author | Jeong, Yujeong | ko |
| dc.contributor.author | Hong, Sungwoo | ko |
| dc.contributor.author | Varani, Gabriele | ko |
| dc.contributor.author | Choi, Byong-Seok | ko |
| dc.date.accessioned | 2013-03-12T17:29:37Z | - |
| dc.date.available | 2013-03-12T17:29:37Z | - |
| dc.date.created | 2012-11-02 | - |
| dc.date.created | 2012-11-02 | - |
| dc.date.issued | 2012-11 | - |
| dc.identifier.citation | MOLECULAR BIOSYSTEMS, v.8, no.11, pp.2857 - 2859 | - |
| dc.identifier.issn | 1742-206X | - |
| dc.identifier.uri | http://hdl.handle.net/10203/103007 | - |
| dc.description.abstract | Aminoglycosides bind to the influenza A virus promoter (vRNA) at submicromolar concentration. The complex structure between the vRNA and neomycin illustrates that binding of neomycin causes a conformational change which would affect further transcription processes. Thus, aminoglycosides represent lead compounds for the discovery of antiviral therapeutics against influenza A virus. | - |
| dc.language | English | - |
| dc.publisher | ROYAL SOC CHEMISTRY | - |
| dc.subject | 16S RIBOSOMAL-RNA | - |
| dc.subject | DECODING REGION | - |
| dc.subject | MESSENGER-RNA | - |
| dc.subject | IN-VITRO | - |
| dc.subject | PROTEIN | - |
| dc.subject | SITE | - |
| dc.subject | REPLICATION | - |
| dc.subject | INHIBITORS | - |
| dc.subject | RECOGNITION | - |
| dc.subject | CONSTRUCTS | - |
| dc.title | Aminoglycoside antibiotics bind to the influenza A virus RNA promoter | - |
| dc.type | Article | - |
| dc.identifier.wosid | 000309481300006 | - |
| dc.identifier.scopusid | 2-s2.0-84867378314 | - |
| dc.type.rims | ART | - |
| dc.citation.volume | 8 | - |
| dc.citation.issue | 11 | - |
| dc.citation.beginningpage | 2857 | - |
| dc.citation.endingpage | 2859 | - |
| dc.citation.publicationname | MOLECULAR BIOSYSTEMS | - |
| dc.identifier.doi | 10.1039/c2mb25333j | - |
| dc.contributor.localauthor | Hong, Sungwoo | - |
| dc.contributor.localauthor | Choi, Byong-Seok | - |
| dc.contributor.nonIdAuthor | Ko, Junsang | - |
| dc.contributor.nonIdAuthor | Park, Chin-Ju | - |
| dc.contributor.nonIdAuthor | Kim, Meehyein | - |
| dc.contributor.nonIdAuthor | Varani, Gabriele | - |
| dc.type.journalArticle | Article | - |
| dc.subject.keywordPlus | 16S RIBOSOMAL-RNA | - |
| dc.subject.keywordPlus | DECODING REGION | - |
| dc.subject.keywordPlus | MESSENGER-RNA | - |
| dc.subject.keywordPlus | IN-VITRO | - |
| dc.subject.keywordPlus | PROTEIN | - |
| dc.subject.keywordPlus | SITE | - |
| dc.subject.keywordPlus | REPLICATION | - |
| dc.subject.keywordPlus | INHIBITORS | - |
| dc.subject.keywordPlus | RECOGNITION | - |
| dc.subject.keywordPlus | CONSTRUCTS | - |
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