Structure-activity relationship study of asiatic acid derivatives against beta amyloid (A beta)-induced neurotoxicity

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8 Semi-synthetic derivatives of asiatic acid were prepared and their protective effect against AP-induced neurotoxicity was evaluated. Among them, asiatic acid (2), and 4, 16 showed 97, 92 and 87% of protective effect, respectively. (C) 2000 Elsevier Science Ltd. All rights reserved.
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Issue Date
2000-01
Language
English
Article Type
Article
Keywords

ALZHEIMERS-DISEASE

Citation

BIOORGANIC MEDICINAL CHEMISTRY LETTERS, v.10, no.2, pp.119 - 121

ISSN
0960-894X
DOI
10.1016/S0960-894X(99)00658-7
URI
http://hdl.handle.net/10203/78067
Appears in Collection
BS-Journal Papers(저널논문)
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