Effective method for specific gene silencing using artificial small RNA 인공 작은 RNA를 사용하여 특이 유전자 발현억제를 위한 효과적인 방법

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A nucleic acid molecule comprising a stem-loop structure, a nucleic acid complex comprising the nucleic acid molecule, a composition for delivering a target recognition sequence, and the composition comprising the nucleic acid complex. An artificial small ribonucleic acid of the stem-loop structure stably maintains single-strandedness of a target recognition sequence which interacts with a nucleic acid of interest for a gene of interest of a prokaryote, thereby providing a nucleic acid complex for effective silencing of the gene of interest.
Assignee
KAIST
Country
US (United States)
Issue Date
2017-12-05
Application Date
2015-09-16
Application Number
14855612
Registration Date
2017-12-05
Registration Number
9,834,768
URI
http://hdl.handle.net/10203/256931
Appears in Collection
CH-Patent(특허)
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