Wide dynamic range high-speed three-dimensional quantitative OCT angiography with a hybrid-beam scan

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We demonstrate a novel hybrid-beam scanning-based quantitative optical coherence tomography angiography (OCTA) that provides high-speed wide dynamic range blood flow speed imaging. The hybrid-beam scanning scheme enables multiple OCTA image acquisitions with a wide range of multiple time intervals simultaneously providing wide dynamic range blood flow speed imaging independent of the blood vessel orientation, which was quantified over a speed range of 0.6 similar to 104 mm/s through the blood flow phantom experiments. A fully automated high-speed hybrid-beam scanning-based quantitative OCTA system demonstrates visualization of blood flow speeds in various vessels from the main arteries to capillaries in a 4 mm x 4 mm area (1024 A-lines x 512 B-scans) in vivo in 20 s, showing its potential as a useful imaging tool for various biomedical applications. (C) 2018 Optical Society of America
Publisher
OPTICAL SOC AMER
Issue Date
2018-05
Language
English
Article Type
Article
Keywords

OPTICAL COHERENCE TOMOGRAPHY; AMPLITUDE-DECORRELATION ANGIOGRAPHY; IN-VIVO; FLOW

Citation

OPTICS LETTERS, v.43, no.10, pp.2237 - 2240

ISSN
0146-9592
DOI
10.1364/OL.43.002237
URI
http://hdl.handle.net/10203/242418
Appears in Collection
CS-Journal Papers(저널논문)ME-Journal Papers(저널논문)
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