OPINION Emerging role for the cytoskeleton as an organizer and regulator of translation

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dc.contributor.authorKim, Seyunko
dc.contributor.authorCoulombe, Pierre A.ko
dc.date.accessioned2013-03-11T12:15:57Z-
dc.date.available2013-03-11T12:15:57Z-
dc.date.created2012-03-19-
dc.date.created2012-03-19-
dc.date.issued2010-01-
dc.identifier.citationNATURE REVIEWS MOLECULAR CELL BIOLOGY, v.11, no.1, pp.75 - 81-
dc.identifier.issn1471-0072-
dc.identifier.urihttp://hdl.handle.net/10203/99291-
dc.description.abstractThe cytoskeleton is an intricate and dynamic fibrous network that has an essential role in the generation and regulation of cell architecture and cellular mechanical properties. The cytoskeleton also evolved as a scaffold that supports diverse biochemical pathways. Recent evidence favours the hypothesis that the cytoskeleton participates in the spatial organization and regulation of translation, at both the global and local level, in a manner that is crucial for cellular growth, proliferation and function.-
dc.languageEnglish-
dc.publisherNATURE PUBLISHING GROUP-
dc.subjectELONGATION-FACTOR 1A-
dc.subjectTRANSFER-RNA-SYNTHETASE-
dc.subjectAMINOACYL-TRANSFER-RNA-
dc.subjectMAMMALIAN PROTEIN-SYNTHESIS-
dc.subjectMOUSE EMBRYO FIBROBLASTS-
dc.subjectACTIN-BINDING PROTEIN-
dc.subjectMICE LACKING VIMENTIN-
dc.subjectF-ACTIN-
dc.subjectINTERMEDIATE-FILAMENTS-
dc.subjectMESSENGER-RNA-
dc.titleOPINION Emerging role for the cytoskeleton as an organizer and regulator of translation-
dc.typeArticle-
dc.identifier.wosid000272944700014-
dc.identifier.scopusid2-s2.0-72949113853-
dc.type.rimsART-
dc.citation.volume11-
dc.citation.issue1-
dc.citation.beginningpage75-
dc.citation.endingpage81-
dc.citation.publicationnameNATURE REVIEWS MOLECULAR CELL BIOLOGY-
dc.identifier.doi10.1038/nrm2818-
dc.contributor.localauthorKim, Seyun-
dc.contributor.nonIdAuthorCoulombe, Pierre A.-
dc.type.journalArticleArticle-
dc.subject.keywordPlusELONGATION-FACTOR 1A-
dc.subject.keywordPlusTRANSFER-RNA-SYNTHETASE-
dc.subject.keywordPlusAMINOACYL-TRANSFER-RNA-
dc.subject.keywordPlusMAMMALIAN PROTEIN-SYNTHESIS-
dc.subject.keywordPlusMOUSE EMBRYO FIBROBLASTS-
dc.subject.keywordPlusACTIN-BINDING PROTEIN-
dc.subject.keywordPlusMICE LACKING VIMENTIN-
dc.subject.keywordPlusF-ACTIN-
dc.subject.keywordPlusINTERMEDIATE-FILAMENTS-
dc.subject.keywordPlusMESSENGER-RNA-
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