DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kwon, D | ko |
dc.contributor.author | Choi, Chulhee | ko |
dc.contributor.author | Lee, J | ko |
dc.contributor.author | Kim, KO | ko |
dc.contributor.author | Kim, JD | ko |
dc.contributor.author | Kim, SJ | ko |
dc.contributor.author | Choi, IH | ko |
dc.date.accessioned | 2013-03-04T14:43:48Z | - |
dc.date.available | 2013-03-04T14:43:48Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2001-02 | - |
dc.identifier.citation | JOURNAL OF NEUROIMMUNOLOGY, v.113, no.1, pp.1 - 9 | - |
dc.identifier.issn | 0165-5728 | - |
dc.identifier.uri | http://hdl.handle.net/10203/82983 | - |
dc.description.abstract | Fas expression increases in perinecrotic areas of glioblastoma. In this study the up-regulation of Fas/FasL by oxidative stress was shown. H2O2 exposure increased Fas expression in two astrocytoma cell lines and cells became sensitive to agonistic anti-Fas antibody. FasL was up-regulated in astrocytoma cells. Apoptosis of Molt-4 cells was augmented by astrocytoma cells pretreated with H2O2. Our findings suggest up-regulation of Fas in astrocytoma cells may lead them to be sensitive to apoptosis when cells are in oxidative stress. Whereas, the up-regulation of Fast may render astrocytoma cells cytotoxic to neighboring brain tissues and infiltrating immune cells. (C) 2001 Elsevier Science B.V. All rights reserved. | - |
dc.language | English | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.subject | NF-KAPPA-B | - |
dc.subject | MULTIPLE-SCLEROSIS BRAIN | - |
dc.subject | FAS LIGAND | - |
dc.subject | ENDOTHELIAL-CELLS | - |
dc.subject | DEPENDENT ACTIVATION | - |
dc.subject | NITRIC-OXIDE | - |
dc.subject | GENE | - |
dc.subject | CD95 | - |
dc.subject | INVOLVEMENT | - |
dc.subject | INDUCTION | - |
dc.title | Hydrogen peroxide triggers the expression of Fas/FasL in astrocytoma cell lines and augments apoptosis | - |
dc.type | Article | - |
dc.identifier.wosid | 000166575000001 | - |
dc.identifier.scopusid | 2-s2.0-0035255076 | - |
dc.type.rims | ART | - |
dc.citation.volume | 113 | - |
dc.citation.issue | 1 | - |
dc.citation.beginningpage | 1 | - |
dc.citation.endingpage | 9 | - |
dc.citation.publicationname | JOURNAL OF NEUROIMMUNOLOGY | - |
dc.identifier.doi | 10.1016/S0165-5728(00)00321-0 | - |
dc.contributor.localauthor | Choi, Chulhee | - |
dc.contributor.nonIdAuthor | Kwon, D | - |
dc.contributor.nonIdAuthor | Lee, J | - |
dc.contributor.nonIdAuthor | Kim, KO | - |
dc.contributor.nonIdAuthor | Kim, JD | - |
dc.contributor.nonIdAuthor | Kim, SJ | - |
dc.contributor.nonIdAuthor | Choi, IH | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | astrocytoma cell lines | - |
dc.subject.keywordAuthor | H2O2 | - |
dc.subject.keywordAuthor | FaS | - |
dc.subject.keywordAuthor | FasL | - |
dc.subject.keywordAuthor | apoptosis | - |
dc.subject.keywordPlus | NF-KAPPA-B | - |
dc.subject.keywordPlus | MULTIPLE-SCLEROSIS BRAIN | - |
dc.subject.keywordPlus | FAS LIGAND | - |
dc.subject.keywordPlus | ENDOTHELIAL-CELLS | - |
dc.subject.keywordPlus | DEPENDENT ACTIVATION | - |
dc.subject.keywordPlus | NITRIC-OXIDE | - |
dc.subject.keywordPlus | GENE | - |
dc.subject.keywordPlus | CD95 | - |
dc.subject.keywordPlus | INVOLVEMENT | - |
dc.subject.keywordPlus | INDUCTION | - |
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