Application of sulfur ylide mediated epoxidations in the asymmetric synthesis of beta-hydroxy-delta-lactones. Synthesis of a mevinic acid analogue and (+)-prelactone B
Catalytic and stoichiometric asymmetric sulfur ylide reactions were employed to prepare alkyl-aryl epoxide intermediates in a convergent manner. These epoxides were utilized in efficient syntheses of the mevinic acid analogue 1 and prelactone B. (C) 2004 Elsevier Ltd. All rights reserved.
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Issue Date
- 2004-10
- Language
- English
- Article Type
- Article
- Keywords
IN-SITU GENERATION; PRELACTONE-B; ENANTIOSELECTIVE SYNTHESIS; 3-HYDROXY-3-METHYLGLUTARYL-COENZYME-A REDUCTASE; PHOSPHAZENE BASE; DIAZO-COMPOUNDS; EPOXIDES; (+)-COMPACTIN; INHIBITORS; MEVINOLIN
- Citation
TETRAHEDRON, v.60, no.43, pp.9725 - 9733
- ISSN
- 0040-4020
- Appears in Collection
- CH-Journal Papers(저널논문)
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